Acetylcholine
- Generic Name
- Acetylcholine
- Brand Names
- Miochol
- Drug Type
- Small Molecule
- Chemical Formula
- C7H16NO2
- CAS Number
- 51-84-3
- Unique Ingredient Identifier
- N9YNS0M02X
- Background
A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, bu...
- Indication
Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.
- Associated Conditions
- -
- Associated Therapies
- -
Blood Markers for Inflammation and Coronary Artery Vasoreactivity Testing in Patients With Chest Pain and Normal Coronary Arteries
- Conditions
- Interventions
- First Posted Date
- 2010-07-15
- Last Posted Date
- 2011-02-23
- Lead Sponsor
- St George's Healthcare NHS Trust
- Target Recruit Count
- 50
- Registration Number
- NCT01162824
- Locations
- 🇬🇧
Department of Cardiology, St George's Healthcare NHS Trust, London, England, United Kingdom
Bevacizumab and Endothelium Dependent Vasodilation
- Conditions
- Interventions
- First Posted Date
- 2010-05-19
- Last Posted Date
- 2013-01-10
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 24
- Registration Number
- NCT01125943
- Locations
- 🇳🇱
Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
The Effects of C-type Natriuretic Peptide on Human Forearm Blood Vessels
- Conditions
- Interventions
- First Posted Date
- 2010-02-25
- Last Posted Date
- 2020-05-05
- Lead Sponsor
- Queen Mary University of London
- Registration Number
- NCT01075776
- Locations
- 🇬🇧
Queen Mary University London, London, United Kingdom
Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation
- Conditions
- Interventions
- First Posted Date
- 2009-05-14
- Last Posted Date
- 2010-08-10
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 12
- Registration Number
- NCT00901719
- Locations
- 🇬🇧
Clincial Research Facility, Royal Infirmary of Edinburgh, 51 Little France Cresc, Edinburgh, United Kingdom
Niacin to Improve Blood Flow in People With Sickle Cell Disease
- Conditions
- Interventions
- First Posted Date
- 2007-07-30
- Last Posted Date
- 2020-09-10
- Target Recruit Count
- 30
- Registration Number
- NCT00508989
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
🇺🇸Howard University Hospital, Washington, District of Columbia, United States
Model System for Transient Forearm Blood Vessel Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2007-03-29
- Last Posted Date
- 2022-08-09
- Target Recruit Count
- 6
- Registration Number
- NCT00453531
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Sildenafil to Treat HIV-Associated Pulmonary Hypertension
- Conditions
- First Posted Date
- 2006-05-18
- Last Posted Date
- 2019-12-17
- Target Recruit Count
- 20
- Registration Number
- NCT00327080
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
The Role of Nitrite in Preconditioning Mediated Tolerance to Ischemic Stress
- Conditions
- First Posted Date
- 2005-11-07
- Last Posted Date
- 2017-07-02
- Target Recruit Count
- 135
- Registration Number
- NCT00250185
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Adenosine Receptors Influence Ischemia-Reperfusion Injury
- Conditions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2008-03-28
- Lead Sponsor
- Radboud University Medical Center
- Target Recruit Count
- 8
- Registration Number
- NCT00184847
- Locations
- 🇳🇱
Radboud University Nijmegen Medical Centre/Department of Pharmacology and Toxicology, Nijmegen, Gelderland, Netherlands
Endothelial Hyperpolarization in Humans
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2018-08-15
- Lead Sponsor
- Emory University
- Target Recruit Count
- 174
- Registration Number
- NCT00166166
- Locations
- 🇺🇸
Emory University School of Medicine, Atlanta, Georgia, United States
Drug Development Updates
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