Acetylcholine

Generic Name
Acetylcholine
Brand Names
Miochol
Drug Type
Small Molecule
Chemical Formula
C7H16NO2
CAS Number
51-84-3
Unique Ingredient Identifier
N9YNS0M02X
Background

A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, bu...

Indication

Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.

Associated Conditions
-
Associated Therapies
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Mechanisms of Human Cutaneous Microcirculation in Healthy Volunteers

Completed
Conditions
First Posted Date
2005-09-09
Last Posted Date
2017-11-01
Lead Sponsor
University Hospital, Angers
Target Recruit Count
85
Registration Number
NCT00152724
Locations
🇫🇷

Laboratoire de Physiologie et Explorations Vasculaires - CHU Angers, Angers, France

The Effect of Lopinavir/Ritonavir on Endothelial Function

Phase 1
Completed
Conditions
First Posted Date
2004-01-22
Last Posted Date
2008-03-04
Lead Sponsor
National Institutes of Health Clinical Center (CC)
Target Recruit Count
30
Registration Number
NCT00076414
Locations
🇺🇸

National Institutes of Health Clinical Center (CC), Bethesda, Maryland, United States

Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease

Phase 1
Completed
Conditions
First Posted Date
2003-11-11
Last Posted Date
2019-12-12
Lead Sponsor
National Institutes of Health Clinical Center (CC)
Target Recruit Count
44
Registration Number
NCT00072826
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Nitric Oxide to Improve Blood Flow in Sickle Cell Disease

Phase 2
Completed
Conditions
First Posted Date
2001-02-02
Last Posted Date
2008-03-04
Lead Sponsor
National Institutes of Health Clinical Center (CC)
Target Recruit Count
65
Registration Number
NCT00009581
Locations
🇺🇸

Warren G. Magnuson Clinical Center (CC), Bethesda, Maryland, United States

Study of the Effects of Vitamin C on Patients With Type 2 Diabetes

First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Center for Complementary and Integrative Health (NCCIH)
Target Recruit Count
150
Registration Number
NCT00001870
Locations
🇺🇸

National Center for Complementary and Alternative Medicine (NCCAM), Bethesda, Maryland, United States

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