D-Serine

Generic Name
D-Serine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C3H7NO3
CAS Number
312-84-5
Unique Ingredient Identifier
1K77H2Z9B1
Background

A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem]

Associated Conditions
-
Associated Therapies
-

Safety and Effectiveness of D-serine in Schizophrenia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-05-04
Last Posted Date
2020-10-05
Lead Sponsor
Nathan Kline Institute for Psychiatric Research
Target Recruit Count
55
Registration Number
NCT00322023
Locations
๐Ÿ‡บ๐Ÿ‡ธ

The Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

Yale University School of Medicine, New Haven, Connecticut, United States

๐Ÿ‡บ๐Ÿ‡ธ

The Zucker Hillside Hospital, Glen Oaks, New York, United States

D-Serine Treatment of Negative Symptoms and Cognitive Deficits in Schizophrenia

First Posted Date
2005-10-12
Last Posted Date
2017-05-10
Lead Sponsor
Yale University
Target Recruit Count
104
Registration Number
NCT00237809
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Connecticut Mental Health Center, New Haven, Connecticut, United States

๐Ÿ‡บ๐Ÿ‡ธ

VA Connecticut Healthcare System, West Haven, Connecticut, United States

D-Serine for Enhancing Cognitive Retraining for the Treatment of Schizophrenia

Phase 3
Completed
Conditions
First Posted Date
2005-10-12
Last Posted Date
2012-06-18
Lead Sponsor
Yale University
Target Recruit Count
72
Registration Number
NCT00237848
Locations
๐Ÿ‡ฎ๐Ÿ‡ณ

National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India

Israel Multicenter D-Serine Study (IMSER) for the Treatment of Schizophrenia

First Posted Date
2005-08-30
Last Posted Date
2006-12-27
Lead Sponsor
Sheba Medical Center
Target Recruit Count
200
Registration Number
NCT00138775
Locations
๐Ÿ‡ฎ๐Ÿ‡ฑ

Shalvata Mental Health Center, Hod Hasharon, Israel

๐Ÿ‡ฎ๐Ÿ‡ฑ

Shaar Menashe Mental Health Center, Shaar Menashe, Israel

๐Ÿ‡ฎ๐Ÿ‡ฑ

Sheba Medical Center, Ramat-Gan, Israel

and more 11 locations
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