Grn163l

Generic Name
Grn163l
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
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Background

GRN163L is a novel anti-cancer drug. It has been characterized preclinically and shown to inhibit telomerase in human tumor cells of many cancer types (including lung, breast, prostate, liver, and early stage of human breast cancer), in both cell culture systems and animal models. Study of this drug shows the its potential utility in the treatment of patient...

Indication

Investigated for use/treatment in leukemia (lymphoid) and solid tumors.

Associated Conditions
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Associated Therapies
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A Study of GRN163L With Paclitaxel and Bevacizumab to Treat Patients With Locally Recurrent Or Metastatic Breast Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-08-11
Last Posted Date
2015-12-24
Lead Sponsor
Geron Corporation
Target Recruit Count
24
Registration Number
NCT00732056
Locations
🇺🇸

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States

🇺🇸

Ingalls Memorial Hospital, Harvey, Illinois, United States

Safety and Dose Study of GRN163L to Treat Patients With Chronic Lymphoproliferative Disease(CLD)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2005-07-27
Last Posted Date
2015-12-24
Lead Sponsor
Geron Corporation
Target Recruit Count
48
Registration Number
NCT00124189
Locations
🇺🇸

Long Island Jewish Medical Center, New Hyde Park, New York, United States

🇺🇸

Roswell Park Cancer Center, Buffalo, New York, United States

🇺🇸

The Ohio State University James Cancer Hospital, Columbus, Ohio, United States

and more 5 locations
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