Mitoquinone

Generic Name
Mitoquinone
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C37H44O4P
CAS Number
444890-41-9
Unique Ingredient Identifier
47BYS17IY0
Background

Mitoquinone is based on a novel technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to a thousand fold. In 2004, a genomic study of hereditary early-onset Parkinson's disease demonstrated a direct molecular link between mitochondrial dysfunction and the pathogenesis of Parkinson's disease. Mitochondrial dysfunction also has been shown to represent an early critical event in the pathogenesis of the sporadic form of Parkinson's disease. Clinical studies by the Parkinson's Study Group show that very high doses of an antioxidant called Coenzyme Q (which Mitoquinone effectively targets into mitochondria) appear to slow the progression of Parkinson's disease symptoms.

Indication

Investigated for use/treatment in hepatitis (viral, C) and parkinson's disease.

Associated Conditions
-
Associated Therapies
-

The Impact of Chronic Mitochondrial Antioxidant Supplementation on CardiovascularToxicity in Breast Cancer Patients

Not Applicable
Conditions
Interventions
First Posted Date
2021-12-07
Last Posted Date
2022-04-08
Lead Sponsor
D'Or Institute for Research and Education
Target Recruit Count
44
Registration Number
NCT05146843

MitoQ for Fatigue in Multiple Sclerosis

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2017-05-25
Last Posted Date
2023-04-05
Lead Sponsor
Oregon Health and Science University
Target Recruit Count
9
Registration Number
NCT03166800
Locations
🇺🇸

Oregon Health & Science University, Portland, Oregon, United States

© Copyright 2024. All Rights Reserved by MedPath