AT9283

Generic Name
AT9283
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C19H23N7O2
CAS Number
896466-04-9
Unique Ingredient Identifier
XAV9KYN9WL
Background

AT9283 is an aurora Kinase inhibitor developed by Astex Therapeutics for the treatment of cancer. It was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.

Indication

Investigated for use/treatment in cancer/tumors (unspecified), leukemia (myeloid), and solid tumors.

Associated Conditions
-
Associated Therapies
-

A Study of AT9283 in Patients With Relapsed or Refractory Multiple Myeloma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-06-17
Last Posted Date
2023-08-04
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
8
Registration Number
NCT01145989
Locations
🇨🇦

Atlantic Health Sciences Corporation, Saint John, New Brunswick, Canada

🇨🇦

Cross Cancer Institute, Edmonton, Alberta, Canada

🇨🇦

QEII Health Sciences Center, Halifax, Nova Scotia, Canada

and more 3 locations

Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemias

First Posted Date
2007-08-30
Last Posted Date
2024-08-02
Lead Sponsor
Astex Pharmaceuticals, Inc.
Target Recruit Count
48
Registration Number
NCT00522990
Locations
🇺🇸

The University of Texas, MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

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