SF1126

Generic Name
SF1126
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
DL0Q912033
Background

SF1126 is an integrin-targeted PI3 kinase inhibitor.

Indication

For the treatment of various forms of cancer.

Associated Conditions
-
Associated Therapies
-

Phase 1 Study of SF1126 in Combination With Nivolumab in Patients With Advanced Hepatocellular Carcinoma

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2017-02-23
Last Posted Date
2022-05-18
Lead Sponsor
SignalRX Pharmaceuticals, Inc.
Target Recruit Count
7
Registration Number
NCT03059147
Locations
๐Ÿ‡บ๐Ÿ‡ธ

UC San Diego Moores Cancer Center, La Jolla, California, United States

SF1126 in Recurrent or Progressive SCCHN and Mutations in PIK3CA Gene and/or PI-3 Kinase Pathway Genes

First Posted Date
2015-12-31
Last Posted Date
2018-07-11
Lead Sponsor
Ezra Cohen
Target Recruit Count
1
Registration Number
NCT02644122
Locations
๐Ÿ‡บ๐Ÿ‡ธ

UC San Diego Moores Cancer Center, La Jolla, California, United States

SF1126 for Patients With Relapsed or Refractory Neuroblastoma

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2015-01-13
Last Posted Date
2018-08-20
Lead Sponsor
New Approaches to Neuroblastoma Therapy Consortium
Target Recruit Count
4
Registration Number
NCT02337309
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Childrens Hospital Boston, Dana-Farber Cancer Institute., Boston, Massachusetts, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Chicago Comer Children's Hospital, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus, Atlanta, Georgia, United States

and more 8 locations

A Dose Escalation Study of SF1126, a PI3 Kinase (PI3K) Inhibitor, Given By Intravenous (IV) Infusion in Patients With Solid Tumors

First Posted Date
2009-05-22
Last Posted Date
2013-06-13
Lead Sponsor
Semafore Pharmaceuticals
Target Recruit Count
44
Registration Number
NCT00907205
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States

๐Ÿ‡บ๐Ÿ‡ธ

Scottsdale Clinical Research Institute, Scottsdale, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Arizona Cancer Center, Tucson, Arizona, United States

and more 1 locations
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