Anecortave acetate

Generic Name
Anecortave acetate
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C23H30O5
CAS Number
7753-60-8
Unique Ingredient Identifier
Y0PC411K4T
Background

Anecortave acetate (Retaane) is an analog of cortisol acetate; among the modifications to the steroid are the removal of the 11รŸ hydroxyl OH group and an addition of a 21-acetate group. As a result of these modifications, anecortave acetate lacks the typical antiinflammatory and immunosuppressive properties of glucocorticoids.Alcon Inc. is developing and mar...

Indication

Investigated for use/treatment in glaucoma and macular degeneration.

Associated Conditions
-
Associated Therapies
-

Anecortave Acetate Injection to Treat Steroid-responsive Intraocular Pressure Increase in Cornea Transplant Patients

First Posted Date
2009-04-20
Last Posted Date
2018-08-14
Lead Sponsor
Cornea Research Foundation of America
Target Recruit Count
7
Registration Number
NCT00884039
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Price Vision Group, Indianapolis, Indiana, United States

A Multi-Dose Study With a Treatment for Open-Angle Glaucoma

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2008-06-26
Last Posted Date
2012-05-30
Lead Sponsor
Alcon Research
Registration Number
NCT00705770

Prophylactic Anecortave Acetate in Patients With a Retisert Implant

Phase 1
Completed
Conditions
Interventions
First Posted Date
2007-12-11
Last Posted Date
2012-06-05
Lead Sponsor
Texas Retina Associates
Target Recruit Count
12
Registration Number
NCT00570479
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Texas Retina Associates, Arlington, Texas, United States

Treatment of Chronic Central Serous Chorioretinopathy With Open-Label Anecortave Acetate

First Posted Date
2007-06-21
Last Posted Date
2012-10-25
Lead Sponsor
Manhattan Eye, Ear & Throat Hospital
Target Recruit Count
5
Registration Number
NCT00489840
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Manhattan Eye, ear & Throat Institute, New York, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

Vitreous-Retina-Macula Consultants of New York,PC, New York, New York, United States

Treatment of Patients With Age-Related Macular Degeneration With Anecortave Acetate

First Posted Date
2006-07-10
Last Posted Date
2010-01-15
Lead Sponsor
University of Iowa
Registration Number
NCT00349739
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Iowa Hospitals and Clinics, Ophthalmology, Iowa City, Iowa, United States

Anecortave Acetate Versus Placebo in AMD Patients Following PDT

Phase 2
Completed
Conditions
First Posted Date
2006-06-30
Last Posted Date
2008-08-05
Lead Sponsor
Alcon Research
Target Recruit Count
136
Registration Number
NCT00346866
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Facility, Beachwood, Ohio, United States

Treatment of Retinal Vein Occlusion (RVO) With Open-Label Anecortave Acetate (15mg.)

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2005-09-21
Last Posted Date
2009-02-04
Lead Sponsor
Manhattan Eye, Ear & Throat Hospital
Registration Number
NCT00211354
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Manhattan Eye, Ear & Throat Hospital, New York, New York, United States

Treatment of Idiopathic Perifoveal Telangiectasia (IPT) With Open-Label Anecortave Acetate (15mg.).

Phase 2
Completed
Conditions
First Posted Date
2005-09-21
Last Posted Date
2009-02-04
Lead Sponsor
Manhattan Eye, Ear & Throat Hospital
Target Recruit Count
5
Registration Number
NCT00211328
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Manhattan Eye, Ear & Throat Hospital, New York, New York, United States

Treatment of Radiation Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)

Phase 2
Terminated
Conditions
First Posted Date
2005-09-21
Last Posted Date
2007-06-21
Lead Sponsor
Manhattan Eye, Ear & Throat Hospital
Target Recruit Count
2
Registration Number
NCT00211367
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Manhattan Eye, Ear & Throat Hospital, New York, New York, United States

Treatment of Conditions With Open Label-Anecortave Acetate Sterile Suspension ( 15mg.) Where Lesions do Not Meet Acceptable Criteria for Standard Care.

First Posted Date
2005-09-21
Last Posted Date
2007-05-07
Lead Sponsor
Manhattan Eye, Ear & Throat Hospital
Target Recruit Count
5
Registration Number
NCT00211484
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Manhattan Eye, Ear & Throat Hospital, New York, New York, United States

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