GI-4000

Generic Name
GI-4000
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
-
Background

A vaccine containing a heat-killed recombinant Saccharomyces cerevisiae yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors, with potential immunostimulant and antitumor activity.

Indication

Investigated for use/treatment in pancreatic cancer.

Associated Conditions
-
Associated Therapies
-
Clinical Trials
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First Posted Date
2018-06-20
Last Posted Date
2024-12-11
Lead Sponsor
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Target Recruit Count
2
Registration Number
NCT03563157
Locations
🇺🇸

Chan Soon-Shiong Institute for Medicine, El Segundo, California, United States

QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

First Posted Date
2017-11-01
Last Posted Date
2024-12-12
Lead Sponsor
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Target Recruit Count
6
Registration Number
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Locations
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Chan Soon-Shiong Institute for Medicine, El Segundo, California, United States

A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI

Phase 2
Terminated
Conditions
Colon Cancer
Interventions
Drug: chemotherapy and GI-4000
Drug: GI-4000
First Posted Date
2011-03-25
Last Posted Date
2016-08-15
Lead Sponsor
Georgetown University
Target Recruit Count
11
Registration Number
NCT01322815
Locations
🇺🇸

Georgetown University, Washington, District of Columbia, United States

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