Omega-3-acid ethyl esters
- Generic Name
- Omega-3-acid ethyl esters
- Brand Names
- Lovaza, Omtryg
- Drug Type
- Small Molecule
- CAS Number
- 308081-97-2
- Unique Ingredient Identifier
- D87YGH4Z0Q
- Background
Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand name Lovaza.
- Indication
Omega-3-Acid Ethyl Esters capsules, USP are indicated as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia (HTG).
- Associated Conditions
- Severe Hypertriglyceridemia (sHTG)
Low Dose Tamoxifen With or Without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
- Conditions
- Breast Atypical HyperplasiaBreast CarcinomaBreast Ductal Carcinoma In SituBreast Lobular Carcinoma In Situ
- Interventions
- Procedure: Biospecimen CollectionProcedure: MammographyOther: Questionnaire AdministrationProcedure: Random Periareolar Fine-Needle Aspiration
- First Posted Date
- 2024-01-08
- Last Posted Date
- 2025-05-13
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 66
- Registration Number
- NCT06195306
- Locations
- 🇺🇸
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
🇺🇸University of Kansas Cancer Center, Kansas City, Kansas, United States
🇺🇸Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
Immunonutrition for Diabetic Foot Ulcers
- Conditions
- Diabetes MellitusDiabetic Peripheral NeuropathyDiabetic Foot Ulcer
- Interventions
- First Posted Date
- 2022-03-16
- Last Posted Date
- 2024-12-27
- Lead Sponsor
- Prisma Health-Midlands
- Target Recruit Count
- 1
- Registration Number
- NCT05281562
- Locations
- 🇺🇸
Prisma Health, Columbia, South Carolina, United States
Pro-Resolving Mediators in Acute Inflammation in Humans
- Conditions
- BlisterInflammation; SkinResolution
- Interventions
- First Posted Date
- 2020-03-16
- Last Posted Date
- 2022-05-26
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 19
- Registration Number
- NCT04308889
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers
- Conditions
- Lung DiseasesLung Cancer, Protection Against
- Interventions
- First Posted Date
- 2018-07-26
- Last Posted Date
- 2025-03-11
- Target Recruit Count
- 75
- Registration Number
- NCT03598309
- Locations
- 🇺🇸
H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States
QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy
- Conditions
- Pancreatic Cancer
- Interventions
- Biological: ALT-803Biological: ETBX-011Biological: GI-4000Biological: haNK for infusionBiological: avelumabBiological: bevacizumabProcedure: SBRT
- First Posted Date
- 2017-12-29
- Last Posted Date
- 2024-05-22
- Lead Sponsor
- ImmunityBio, Inc.
- Target Recruit Count
- 4
- Registration Number
- NCT03387098
- Locations
- 🇺🇸
Chan Soon-Shiong Institute for Medicine, El Segundo, California, United States
QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy
- Conditions
- Pancreatic Cancer
- Interventions
- First Posted Date
- 2017-11-01
- Last Posted Date
- 2024-12-12
- Lead Sponsor
- ImmunityBio, Inc.
- Target Recruit Count
- 6
- Registration Number
- NCT03329248
- Locations
- 🇺🇸
Chan Soon-Shiong Institute for Medicine, El Segundo, California, United States
QUILT-3.048: NANT Urothelial Cancer Vaccine: Combination Immunotherapy in Subjects With Urothelial Cancer Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy
- Conditions
- Urothelial Carcinoma
- Interventions
- Drug: 5Fluorouracil (5-FU)Radiation: Stereotactic Body Radiation Therapy
- First Posted Date
- 2017-06-23
- Last Posted Date
- 2025-02-21
- Lead Sponsor
- ImmunityBio, Inc.
- Registration Number
- NCT03197571
QUILT-3.049: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Combination Immunotherapy in Subjects With TNBC Who Have Progressed on or After Anthracycline-based Chemotherapy
- Conditions
- Triple Negative Breast Cancer
- Interventions
- Radiation: Stereotactic Body Radiation Therapy
- First Posted Date
- 2017-06-05
- Last Posted Date
- 2025-02-21
- Lead Sponsor
- ImmunityBio, Inc.
- Registration Number
- NCT03175666
QUILT-3.047: NANT Head and Neck Squamous Cell Carcinoma (HNSCC) Vaccine: Combination Immunotherapy in Subjects With HNSCC Who Have Progressed on or After Chemotherapy and PD-1/PD-L1 Therapy
- Conditions
- Head and Neck Squamous Cell Carcinoma
- Interventions
- Radiation: Stereotactic Body Radiation Therapy
- First Posted Date
- 2017-05-30
- Last Posted Date
- 2025-02-24
- Lead Sponsor
- ImmunityBio, Inc.
- Registration Number
- NCT03169764
QUILT-3.052: NANT Non-Hodgkin Lymphoma (NHL) Vaccine: Combination Immunotherapy in Subjects With Relapsed CD20-positive NHL
- Conditions
- Non Hodgkin Lymphoma
- Interventions
- First Posted Date
- 2017-05-30
- Last Posted Date
- 2025-02-24
- Lead Sponsor
- ImmunityBio, Inc.
- Registration Number
- NCT03169790
Drug Development Updates
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