Omega-3-acid ethyl esters
- Generic Name
- Omega-3-acid ethyl esters
- Brand Names
- Lovaza, Omtryg
- Drug Type
- Small Molecule
- CAS Number
- 308081-97-2
- Unique Ingredient Identifier
- D87YGH4Z0Q
- Background
Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand name Lovaza.
- Indication
Omega-3-Acid Ethyl Esters capsules, USP are indicated as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia (HTG).
- Associated Conditions
- Severe Hypertriglyceridemia (sHTG)
Human Immunodeficiency Virus (HIV), Arterial Dysfunction, Lipids, Lovaza (HALO) Trial
- First Posted Date
- 2008-11-21
- Last Posted Date
- 2019-09-11
- Lead Sponsor
- Tufts University
- Target Recruit Count
- 41
- Registration Number
- NCT00795717
- Locations
- 🇺🇸
Tufts University School of Medicine, Boston, Massachusetts, United States
Effects of Fish Oil on Post Ablation Arrhythmias
- Conditions
- Atrial Fibrillation
- Interventions
- First Posted Date
- 2008-11-14
- Last Posted Date
- 2017-09-12
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 12
- Registration Number
- NCT00791089
- Locations
- 🇺🇸
University of Michigan Cardiovascular Center, Ann Arbor, Michigan, United States
The Effects of Omega-3 Fatty Acids on Aspirin Resistance
- Conditions
- Increased Drug Resistance
- Interventions
- First Posted Date
- 2008-10-15
- Last Posted Date
- 2012-11-06
- Lead Sponsor
- University of Rochester
- Target Recruit Count
- 27
- Registration Number
- NCT00771914
- Locations
- 🇺🇸
University of Rochester School of Medicine and Dentistry, Rochester, New York, United States
Women With Chest Pain and Normal Coronary Arteries Study
- Conditions
- Chest Pain
- Interventions
- First Posted Date
- 2008-08-28
- Last Posted Date
- 2023-12-12
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 3
- Registration Number
- NCT00743197
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
Nutritional Supplements and Hormonal Manipulations for Breast Cancer Prevention
- Conditions
- Breast Cancer
- Interventions
- Dietary Supplement: Lovaza 4gm oral
- First Posted Date
- 2008-07-28
- Last Posted Date
- 2018-11-01
- Lead Sponsor
- Milton S. Hershey Medical Center
- Target Recruit Count
- 266
- Registration Number
- NCT00723398
- Locations
- 🇺🇸
Penn State Hershey Medical Center, Hershey, Pennsylvania, United States
Study of Fish Oil to Reduce ALT Levels in Adolescents
- Conditions
- Non-alcoholic Fatty Liver DiseaseFatty Liver
- Interventions
- Drug: Placebo
- First Posted Date
- 2008-06-10
- Last Posted Date
- 2016-01-29
- Lead Sponsor
- Boston University
- Target Recruit Count
- 3
- Registration Number
- NCT00694746
- Locations
- 🇺🇸
Boston University Medical Center, Boston, Massachusetts, United States
Trial of Lovaza in Adolescents With Mild to Moderately Elevated Triglycerides
- First Posted Date
- 2008-05-06
- Last Posted Date
- 2013-05-29
- Lead Sponsor
- Boston Children's Hospital
- Target Recruit Count
- 25
- Registration Number
- NCT00672633
- Locations
- 🇺🇸
Children's Hospital Boston, Boston, Massachusetts, United States
Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM
- Conditions
- Diabetes Mellitus, Type II
- Interventions
- First Posted Date
- 2007-12-20
- Last Posted Date
- 2018-08-31
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 78
- Registration Number
- NCT00577590
- Locations
- 🇺🇸
Washington University in St. Louis, Saint Louis, Missouri, United States
Lovaza Therapy of Peripheral Arterial Disease
- First Posted Date
- 2007-12-07
- Last Posted Date
- 2018-05-07
- Lead Sponsor
- University of Virginia
- Registration Number
- NCT00569686
- Locations
- 🇺🇸
University of Virginia Health System, Charlottesville, Virginia, United States
Lovaza's Effect on the Activation of Platelets
- First Posted Date
- 2007-08-13
- Last Posted Date
- 2013-07-09
- Lead Sponsor
- Invitrox
- Target Recruit Count
- 43
- Registration Number
- NCT00515541
Drug Development Updates
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