Seliciclib

Generic Name
Seliciclib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C19H26N6O
CAS Number
186692-46-6
Unique Ingredient Identifier
0ES1C2KQ94
Background

R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated cells. Developed by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.

Indication

Investigated for use/treatment in breast cancer, lung cancer, lymphoma (unspecified), multiple myeloma, leukemia (lymphoid), and cancer/tumors (unspecified).

Associated Conditions
-
Associated Therapies
-
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