Atrasentan

Generic Name
Atrasentan
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C29H38N2O6
CAS Number
173937-91-2
Unique Ingredient Identifier
V6D7VK2215
Background

Atrasentan is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called endothelin-1 protein receptor antagonists. It is a novel, selective endothelin A receptor antagonist (SERA).

Indication

Investigated for use/treatment in prostate cancer and cancer/tumors (unspecified).

Associated Conditions
-
Associated Therapies
-

Safety and Efficacy of Atrasentan in Men With Hormone Naive Prostate Cancer Exhibiting Early Signs of Biochemical Failure

Phase 2
Completed
Conditions
First Posted Date
2002-06-04
Last Posted Date
2006-08-15
Lead Sponsor
Abbott
Target Recruit Count
200
Registration Number
NCT00038662
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Carolinas Medical Centre, Charlotte,, North Carolina, United States

๐Ÿ‡บ๐Ÿ‡ธ

Urologic Specialists Of Oklahoma, Inc., Tulsa,, Oklahoma, United States

๐Ÿ‡บ๐Ÿ‡ธ

Center for Urologic Care, West Reading, Pennsylvania, United States

and more 36 locations

A Study of Atrasentan in Men With Metastatic, Hormone-Refractory Prostate Cancer

Phase 3
Completed
Conditions
First Posted Date
2002-05-13
Last Posted Date
2006-08-15
Lead Sponsor
Abbott
Target Recruit Count
1000
Registration Number
NCT00036543
Locations
๐Ÿ‡จ๐Ÿ‡ฆ

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

๐Ÿ‡บ๐Ÿ‡ธ

Alaska Clinical Research Center, LLC, Anchorage, Alaska, United States

๐Ÿ‡บ๐Ÿ‡ธ

Clinical Physiology Associates, Fort Myers, Florida, United States

and more 229 locations

Study of Atrasentan in Men With Non-Metastatic, Hormone-Refractory Prostate Cancer

Phase 3
Completed
Conditions
First Posted Date
2002-05-13
Last Posted Date
2007-08-15
Lead Sponsor
Abbott
Target Recruit Count
941
Registration Number
NCT00036556
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Ntouch Research Corporation, Dallas, Texas, United States

๐Ÿ‡จ๐Ÿ‡ฆ

Princess Margaret Hospital, Toronto, Ontario, Canada

๐Ÿ‡บ๐Ÿ‡ธ

UCLA School of Medicine, Los Angeles, California, United States

and more 230 locations
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