MedPath

Calcitonin gene-related peptide

Generic Name
Calcitonin gene-related peptide
Drug Type
Biotech
CAS Number
83652-28-2
Unique Ingredient Identifier
JHB2QIZ69Z

Overview

A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator. As a potential drug, it has demonstrated in preclinical studies a profile that could make it an ideal anti-asthmatic drug candidate with bronchodilatory, bronchoprotecting and anti-inflammatory properties.

Background

A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator. As a potential drug, it has demonstrated in preclinical studies a profile that could make it an ideal anti-asthmatic drug candidate with bronchodilatory, bronchoprotecting and anti-inflammatory properties.

Indication

Investigated for use/treatment in myocardial infarction, heart disease, and asthma.

Associated Conditions

No associated conditions information available.

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2023/08/30
N/A
Recruiting
2020/10/19
Phase 4
Recruiting
2020/07/01
Not Applicable
UNKNOWN
2020/01/18
Not Applicable
Completed
2019/01/02
Not Applicable
Completed
2018/05/31
Not Applicable
Completed
2018/03/29
Not Applicable
UNKNOWN
2017/05/08
Not Applicable
UNKNOWN
2013/08/16
Not Applicable
Completed
2008/06/02
Not Applicable
Completed

FDA Drug Approvals

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No FDA approvals found for this drug.

EMA Drug Approvals

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No EMA approvals found for this drug.

HSA Drug Approvals

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No HSA approvals found for this drug.

NMPA Drug Approvals

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No NMPA approvals found for this drug.

PPB Drug Approvals

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No PPB approvals found for this drug.

TGA Drug Approvals

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No TGA approvals found for this drug.
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