Pegargiminase

Generic Name
Pegargiminase
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
1394129-74-8
Unique Ingredient Identifier
0B7PYQ9YRT
Background

Pegargiminase is an anticancer agent.

Indication

Investigated for use/treatment in melanoma and hepatocellular carcinoma.

Associated Conditions
-
Associated Therapies
-

Ph 1 Study of ADI PEG 20 in Pediatric Subjects Who Are Argininosuccinate Synthetase (ASS) Deficient

Phase 1
Completed
Conditions
First Posted Date
2012-02-08
Last Posted Date
2014-04-09
Lead Sponsor
Polaris Group
Target Recruit Count
8
Registration Number
NCT01528384
Locations
🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

Ph 1 Trial of ADI-PEG 20 Plus Docetaxel in Solid Tumors With Emphasis on Prostate Cancer and Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2011-12-23
Last Posted Date
2018-09-13
Lead Sponsor
Polaris Group
Target Recruit Count
43
Registration Number
NCT01497925
Locations
🇺🇸

University of California at Davis, Sacramento, California, United States

A Clinical Trial of ADI-PEG 20TM in Patients With Malignant Pleural Mesothelioma

First Posted Date
2011-01-20
Last Posted Date
2014-11-20
Lead Sponsor
Barts & The London NHS Trust
Target Recruit Count
70
Registration Number
NCT01279967
Locations
🇬🇧

The Royal Sussex County Hospital, Brighton, United Kingdom

🇬🇧

Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, United Kingdom

🇬🇧

Hull and East Yorkshire Hospitals NHS Trust,The Princess Royal Hospital, Hull, United Kingdom

and more 4 locations

Testing of ADI-PEG in Hepatocellular Carcinoma

Phase 2
Completed
Conditions
First Posted Date
2003-03-27
Last Posted Date
2015-03-25
Lead Sponsor
FDA Office of Orphan Products Development
Target Recruit Count
34
Registration Number
NCT00056992
Locations
🇺🇸

MD Anderson Cancer center, Houston, Texas, United States

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