Danaparoid
- Generic Name
- Danaparoid
- Brand Names
- Orgaran
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 308068-55-5
- Unique Ingredient Identifier
- BI6GY4U9CW
- Background
Danaparoid is a low-molecular-weight heparinoid with an average molecular weight of 5500 Daltons consisting of a mixture of glycosaminoglycans . The active constituents are heparan, dermatan and Chondroitin sulfate , and they are isolated from the porcine intestinal mucosa . Danaparoid possesses a potent antithrombic activity that works by inhibiting activat...
- Indication
Indicated for the prophylaxis of post-operative deep venous thrombosis (DVT), which may lead to pulmonary embolism (PE), in patients undergoing elective hip replacement surgery .
- Associated Conditions
- Deep Vein Thrombosis caused by Major Abdominal Surgery, Deep Vein Thrombosis caused by Orthopedic Surgery, Deep Vein Thrombosis caused by Thoracic Surgery, Heparin Induced Thrombocytopenia (HIT), Non-hemorrhagic stroke
- Associated Therapies
- -
Retrospective Registry of Patients With Acute Heparin-induced Thrombocytopenia Type II
Completed
- Conditions
- Interventions
- First Posted Date
- 2011-02-25
- Last Posted Date
- 2017-07-06
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 195
- Registration Number
- NCT01304238
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