Nonoxynol-9
- Generic Name
- Nonoxynol-9
- Brand Names
- Conceptrol, Gynol II, Today Sponge, Vcf Contraceptive
- Drug Type
- Small Molecule
- Chemical Formula
- C33H60O10
- CAS Number
- 26027-38-3
- Unique Ingredient Identifier
- 48Q180SH9T
- Background
Nonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. When present in the vagina during intercourse, they immobilize/inactivate/damage and/or kill sperms without eliciting systemic effects. N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels...
- Indication
Nonoxynol 9 is a surfactant spermicide used for contraception in spermicidal creams, jellies, foams, gel, and lubricants. It is also used in conjuction with other methods of contraception, including condoms, cervical caps and diaphragms.
- Associated Conditions
- -
- Associated Therapies
- Contraceptive sponge therapy
Identification of Novel Biomarkers of Cervicovaginal Mucosal Inflammation
- Conditions
- Interventions
- First Posted Date
- 2012-05-07
- Last Posted Date
- 2015-03-31
- Lead Sponsor
- CONRAD
- Target Recruit Count
- 20
- Registration Number
- NCT01593124
- Locations
- 🇺🇸
Eastern Virginia Medical School CONRAD Clinical Research Center, Norfolk, Virginia, United States
Study of Contraceptive Efficacy & Safety of Phexxiâ„¢ (Previously Known as Amphora) Gel Compared to Conceptrol Vaginal Gel
- First Posted Date
- 2011-03-01
- Last Posted Date
- 2022-07-12
- Lead Sponsor
- Evofem Inc.
- Target Recruit Count
- 3389
- Registration Number
- NCT01306331
- Locations
- 🇺🇸
Wake Research Associates, Raleigh, North Carolina, United States
🇺🇸University of Pennsylvania Medical Center, Reproductive Research Unit, Philadelphia, Pennsylvania, United States
🇺🇸Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, United States
A Pilot Study for Toxicity Evaluation of HIV Rectal Microbicides
- Conditions
- Interventions
- First Posted Date
- 2006-10-18
- Last Posted Date
- 2015-04-01
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 12
- Registration Number
- NCT00389311
- Locations
- 🇺🇸
The Johns Hopkins Hospital, Baltimore, Maryland, United States
A Study of Nonoxynol-9 (N-9) and HIV Infection
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 4400
- Registration Number
- NCT00000926
- Locations
- 🇺🇸
Julia Welch, Research Triangle Park, North Carolina, United States
A Study of the Effects of Advantage 24 on the Rectum
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-10-29
- Target Recruit Count
- 70
- Registration Number
- NCT00000929
- Locations
- 🇺🇸
Univ of Washington, Seattle, Washington, United States
Drug Development Updates
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