Ulipristal
- Generic Name
- Ulipristal
- Brand Names
- Ella, Ellaone, Esmya, ellaOne
- Drug Type
- Small Molecule
- Chemical Formula
- C28H35NO3
- CAS Number
- 159811-51-5
- Unique Ingredient Identifier
- 6J5J15Q2X8
- Background
Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. It also binds to glucocorticoid receptor, however compared to mif...
- Indication
As the product Ella (available in Canada and the US), ulipristal is indicated for use as emergency contraception after unprotected intercourse or possible contraceptive failure when administered within 120 hours (5 days) after unprotected intercourse or a known or suspected contraceptive failure. As the product Fibristal (available in Canada), ulipristal is ...
- Associated Conditions
- Moderate Uterine Fibroids, Severe Uterine Fibroids
- Associated Therapies
- Emergency Contraception
Ulipristal Emergency Contraception Used Before or After Ovulation
- First Posted Date
- 2015-08-07
- Last Posted Date
- 2018-07-30
- Lead Sponsor
- The University of Hong Kong
- Target Recruit Count
- 700
- Registration Number
- NCT02517463
Assess Safety and Efficacy of Vilaprisan in Patients With Uterine Fibroids
- Conditions
- Interventions
- First Posted Date
- 2015-06-09
- Last Posted Date
- 2016-11-22
- Lead Sponsor
- Bayer
- Target Recruit Count
- 120
- Registration Number
- NCT02465814
A Study to Evaluate the Effect of a Contraceptive Vaginal Ring Delivering Ulipristal Acetate Combined With a Single or Repeated Levonorgestrel on Inhibition of Ovulation, Endometrial Changes and Bleeding Patterns in Normal Cycling Women
- First Posted Date
- 2015-05-22
- Last Posted Date
- 2017-08-15
- Lead Sponsor
- Population Council
- Target Recruit Count
- 19
- Registration Number
- NCT02451826
- Locations
- 🇩🇴
Profamilia, Santo Domingo, Dominican Republic
Endometrial Preparation Before Operative Hysteroscopy in Premenopausal Women
- Conditions
- Interventions
- First Posted Date
- 2015-05-12
- Last Posted Date
- 2016-03-09
- Lead Sponsor
- University of Cagliari
- Target Recruit Count
- 50
- Registration Number
- NCT02440750
Ulipristal Acetate 10 mg and Asisted Reproduction
- Conditions
- Interventions
- First Posted Date
- 2015-04-24
- Last Posted Date
- 2020-10-14
- Target Recruit Count
- 2
- Registration Number
- NCT02425878
- Locations
- 🇪🇸
IVI Valencia, Valencia, Spain
Breast Cancer - Anti-Progestin Prevention Study 1
- First Posted Date
- 2015-04-03
- Last Posted Date
- 2023-05-06
- Lead Sponsor
- Manchester University NHS Foundation Trust
- Target Recruit Count
- 24
- Registration Number
- NCT02408770
- Locations
- 🇬🇧
University Hospitals of South Manchester, Manchester, United Kingdom
Ulipristal Acetate Versus GnRH Analogue Treatment Before Hysteroscopic Resection of Uterine Leiomyoma
- First Posted Date
- 2015-02-12
- Last Posted Date
- 2016-11-18
- Lead Sponsor
- University Magna Graecia
- Target Recruit Count
- 146
- Registration Number
- NCT02361879
- Locations
- 🇮🇹
Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
Ulipristal Acetate for the Preoperative Management of Hypoechoic Cellular Leiomyomas
- First Posted Date
- 2015-02-12
- Last Posted Date
- 2016-11-18
- Lead Sponsor
- University Magna Graecia
- Target Recruit Count
- 42
- Registration Number
- NCT02361905
- Locations
- 🇮🇹
Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
The Effect of Ulipristal Acetate (UPA) on Women Ovarian Reserve
- First Posted Date
- 2015-02-12
- Last Posted Date
- 2016-11-18
- Lead Sponsor
- University Magna Graecia
- Target Recruit Count
- 73
- Registration Number
- NCT02361892
- Locations
- 🇮🇹
Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
Ulipristal Acetate Versus GnRH Analogue and Myometrial Preservation
- First Posted Date
- 2015-02-06
- Last Posted Date
- 2016-11-18
- Lead Sponsor
- University Magna Graecia
- Target Recruit Count
- 110
- Registration Number
- NCT02357563
- Locations
- 🇮🇹
Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy
Drug Development Updates
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