Aleglitazar
- Generic Name
- Aleglitazar
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C24H23NO5S
- CAS Number
- 475479-34-6
- Unique Ingredient Identifier
- 41T4OAG59U
- Background
Aleglitazar is an investigational drug from the company Hoffmann–La Roche and is currently in a phase III clinical trial called ALECARDIO. It is being investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity. Aleglitazar is an agonist at the peroxisome proliferator-activated receptor (PPAR) for both the PPARα and PPARγ receptor subtypes. In the phase II clinical trial called SYNCHRONY, with type II diabetic patients, aleglitazar was able to control both lipid and glucose levels in a synergistic manner while also having limited side effects and toxicity.
- Indication
Investigated for use in patients with type II diabetes to reduce their risks of cardiovascular mortality and morbidity.
- Associated Conditions
- -
- Associated Therapies
- -
A Study of Aleglitazar in Patients With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2006-10-17
- Last Posted Date
- 2016-11-02
- Lead Sponsor
- Hoffmann-La Roche
- Target Recruit Count
- 332
- Registration Number
- NCT00388518
Drug Development Updates
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