Corticorelin ovine triflutate

Generic Name
Corticorelin ovine triflutate
Brand Names
Acthrel
Drug Type
Biotech
Chemical Formula
-
CAS Number
121249-14-7
Unique Ingredient Identifier
56X54T817Q
Background

Corticorelin, available commercially as corticorelin ovine triflutate (tradename Acthrel), is a synthetic form of the peptide human corticotropin-releasing hormone (hCRH), a potent stimulator of adrenocorticotropic hormone (ACTH) release from the anterior pituitary. Endogenous forms hCRH are involved in the stress response and its main function is stimulatio...

Indication

Corticorelin is indicated for use in differentiating pituitary and ectopic production of ACTH in patients with ACTH-dependent Cushing's syndrome.

Associated Conditions
Pituitary-dependent Cushing's syndrome
Associated Therapies
-

Corticotrophin-releasing Hormone (CRH) Stimulation for 18F-FDG-PET Detection of Pituitary Adenoma in Cushing s Disease

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2020-09-30
Last Posted Date
2024-12-20
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Target Recruit Count
22
Registration Number
NCT04569591
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary Measures

First Posted Date
2012-08-27
Last Posted Date
2018-04-23
Lead Sponsor
University of Michigan
Target Recruit Count
256
Registration Number
NCT01673087
Locations
🇺🇸

University of Michigan Health System, Ann Arbor, Michigan, United States

Effects of Hormone Stimulation on Brain Scans for Cushing s Disease

Early Phase 1
Completed
Conditions
First Posted Date
2011-10-25
Last Posted Date
2018-06-14
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Target Recruit Count
30
Registration Number
NCT01459237
Locations
🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Corticotropin Releasing Hormone (CRH) Responsiveness in Children With Functional Dyspepsia

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2011-06-15
Last Posted Date
2019-05-16
Lead Sponsor
Children's Mercy Hospital Kansas City
Registration Number
NCT01373372
Locations
🇺🇸

Children's Mercy Hospital and Clinics, Kansas City, Missouri, United States

Gender and Neural Substrates of Stress and Craving

Completed
Conditions
Interventions
First Posted Date
2008-09-22
Last Posted Date
2018-05-07
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
19
Registration Number
NCT00756925
Locations
🇺🇸

Clinical Neurosciences Division-Medical University of South Carolina, Charleston, South Carolina, United States

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