Dosulepin

Generic Name: Dosulepin

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₁₉H_₂₁NS

CAS Number: 113-53-1

Unique Ingredient Identifier: W13O82Z7HL

Background: Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. Dosulepin inhibits the reuptake of biogenic ...

Indication: Indicated in the treatment of symptoms of depressive illness, especially where an anti-anxiety effect is required.

Associated Conditions: Anxiety, Depression

Associated Therapies: -

Clinical Trials

Study of the Effect of Antidepressant Drugs on Neurotrophic Factors in Patients With Depression

Completed

Conditions: Depressive Episode

Interventions: Drug: Sertraline
Drug: Dosulepin
Drug: Venlafaxine

First Posted Date: 2017-04-24

Last Posted Date: 2018-07-11

Lead Sponsor: All India Institute of Medical Sciences, Bhubaneswar

Target Recruit Count: 105

Registration Number: NCT03126188

Locations: 🇮🇳
Dept of Psychiatry, Aiims, Bhubaneswar, Bhubaneswar, Odisha, India

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