MedPath

Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen

Generic Name
Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen
Brand Names
Menactra
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
2J57K2523T
Background

Neisseria meningitidis group c capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup c. The vaccine contains N. meningitis serogroup c capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are extracted from Corynebacterium diphtheriae grown in another culture.

Associated Conditions
Invasive Meningococcal Infection caused by Neisseria meningitidis serogroup C
Associated Therapies
-

Pfs230D1M-EPA/AS01 Vaccine, a Transmission Blocking Vaccine Against Plasmodium Falciparum, in an Age De-Escalation Trial of Children and a Family Compound Trial in Mali

Phase 2
Completed
Conditions
Malaria
Interventions
Biological: HAVRIX
Biological: Pfs230D1M-EPA/AS01
Biological: AVAXIM
Biological: TYPHIM Vi (Salmonella typhi vaccine)
Biological: Menactra
First Posted Date
2019-04-17
Last Posted Date
2024-10-22
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
1301
Registration Number
NCT03917654
Locations
🇲🇱

Mrtc/Usttb, Bamako, Mali

Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali

Phase 1
Completed
Conditions
Malaria
Interventions
Biological: Pfs25M-EPA
Biological: Pfs230D1M-EPA
Biological: Engerix-B
Other: AS01
Biological: Menactra
Other: Normal Saline
Drug: Coartem
First Posted Date
2016-10-24
Last Posted Date
2024-12-10
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
301
Registration Number
NCT02942277
Locations
🇲🇱

Bancoumana Malaria Vaccine Center, Bamako, Mali

Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and Mali

Phase 1
Completed
Conditions
Malaria
Interventions
Biological: Pfs25M-EPA/Alhydrogel
Biological: Pfs230D1M-EPA/Alhydrogel
Drug: TWINRIX
Drug: Menactra
First Posted Date
2015-01-08
Last Posted Date
2019-04-11
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
538
Registration Number
NCT02334462
Locations
🇲🇱

Malaria Research and Training Center, Bamako, Mali

🇺🇸

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

© Copyright 2025. All Rights Reserved by MedPath