Psilocybin

Generic Name
Psilocybin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C12H17N2O4P
CAS Number
520-52-5
Unique Ingredient Identifier
2RV7212BP0
Background

Psilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.

Associated Conditions
-
Associated Therapies
-

Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care

First Posted Date
2021-07-06
Last Posted Date
2024-08-27
Lead Sponsor
Yvan Beaussant, MD, MSci
Target Recruit Count
15
Registration Number
NCT04950608
Locations
🇺🇸

Care Dimensions, Danvers, Massachusetts, United States

Phase 1b Study in Patients With Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)

First Posted Date
2021-05-27
Last Posted Date
2022-10-12
Lead Sponsor
Beckley Psytech Limited
Target Recruit Count
4
Registration Number
NCT04905121
Locations
🇬🇧

King's College London, London, United Kingdom

PSilocybin for psYCHological and Existential Distress in PALliative Care (PSYCHED-PAL)

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2021-02-15
Last Posted Date
2024-08-09
Lead Sponsor
Ottawa Hospital Research Institute
Target Recruit Count
20
Registration Number
NCT04754061
Locations
🇨🇦

Bruyere Continuing Care, Ottawa, Ontario, Canada

🇨🇦

The Ottawa Hospital, Ottawa, Ontario, Canada

The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression

Phase 2
Completed
Conditions
Interventions
First Posted Date
2021-02-05
Last Posted Date
2023-11-09
Lead Sponsor
COMPASS Pathways
Target Recruit Count
19
Registration Number
NCT04739865
Locations
🇮🇪

Sheaf House, Tallaght Hospital, Dublin, Ireland

🇺🇸

Kadima Neuropsychiatry Institute, La Jolla, California, United States

Psilocybin for Treatment of Alcohol Use Disorder: a Feasibility Study

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2021-01-22
Last Posted Date
2024-07-12
Lead Sponsor
Anders Fink-Jensen, MD, DMSci
Target Recruit Count
10
Registration Number
NCT04718792
Locations
🇩🇰

Psychiatric Center Copenhagen, Copenhagen, Frederiksberg, Denmark

Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-12-17
Last Posted Date
2024-08-06
Lead Sponsor
Central Institute of Mental Health, Mannheim
Target Recruit Count
144
Registration Number
NCT04670081
Locations
🇩🇪

Central Institute of Mental Health (CIMH), Mannheim, Germany

🇩🇪

Charité Berlin, Campus Mitte, Department of Psychiatry and Psychotherapy, Berlin, Germany

Evaluation of Psilocybin in Anorexia Nervosa: Safety and Efficacy

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-12-10
Last Posted Date
2022-07-25
Lead Sponsor
University of California, San Diego
Target Recruit Count
16
Registration Number
NCT04661514
Locations
🇺🇸

Altman Clinical and Translational Research Institute, La Jolla, California, United States

Safety and Efficacy of Psilocybin for Body Dysmorphic Disorder

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-12-07
Last Posted Date
2023-03-13
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
12
Registration Number
NCT04656301
Locations
🇺🇸

New York State Psychiatric Institute, 1051 Riverside Drive, New York, New York, United States

The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density

First Posted Date
2020-11-16
Last Posted Date
2024-04-19
Lead Sponsor
Section for Affective Disorders; Northern Stockholm Psychiatry
Target Recruit Count
35
Registration Number
NCT04630964
Locations
🇸🇪

Northern Stockholm Spychiatry Clinic, Stockholm, Sweden

Psilocybin Treatment of Major Depressive Disorder With Co-occurring Alcohol Use Disorder

First Posted Date
2020-11-09
Last Posted Date
2024-12-19
Lead Sponsor
Johns Hopkins University
Target Recruit Count
90
Registration Number
NCT04620759
Locations
🇺🇸

Johns Hopkins Center for Psychedelic and Consciousness Research, Baltimore, Maryland, United States

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