Lasmiditan

Generic Name
Lasmiditan
Brand Names
Reyvow, Rayvow
Drug Type
Small Molecule
Chemical Formula
C19H18F3N3O2
CAS Number
439239-90-4
Unique Ingredient Identifier
760I9WM792
Background

Lasmiditan is an oral medication used in the termination of migraine headaches that was first approved for use in the United States in October 2019. It was also approved by the European Commission on August 17, 2022.
...

Indication

Lasmiditan is indicated for the acute treatment of migraine with or without aura in adults.

Associated Conditions
Migraine Headache, With or Without Aura
Associated Therapies
-

Ditan Acute tReatments: Effectiveness and Tolerability (DART)

First Posted Date
2023-06-15
Last Posted Date
2023-12-08
Lead Sponsor
University of Florence
Target Recruit Count
100
Registration Number
NCT05903040
Locations
🇮🇹

SOD Centro Cefalee e Farmacologia Clinica, AOU Careggi, Florence, Italy

🇮🇹

IRCCS National Neurological Institute "C. Mondino" Foundation, Pavia, Italy

A Study to Compare Two Different Formulations of Lasmiditan in Healthy Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2021-05-11
Last Posted Date
2023-03-23
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
47
Registration Number
NCT04881747
Locations
🇺🇸

Covance Dallas, Dallas, Texas, United States

A Study of Lasmiditan in Healthy Volunteers

First Posted Date
2021-02-11
Last Posted Date
2024-02-01
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
97
Registration Number
NCT04749914
Locations
🇸🇬

Lilly Centre for Clinical Pharmacology, Singapore, Singapore

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2020-05-20
Last Posted Date
2024-12-10
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1000
Registration Number
NCT04396574
Locations
🇺🇸

Rochester Clinical Research, Inc., Rochester, New York, United States

🇧🇪

Ziekenhuis Oost-Limburg, Campus St.-Jan, Genk, Limburg, Belgium

🇮🇹

IRCCS Istituto Neurologico Carlo Besta, Milano, Lombardia, Italy

and more 170 locations

A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2020-05-20
Last Posted Date
2024-12-06
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1633
Registration Number
NCT04396236
Locations
🇪🇸

Hospital Universitario La Paz-NEURO, Madrid, Spain

🇬🇧

Queen's Medical Centre, Nottingham University Hospitals, Nottingham, Nottinghamshire, United Kingdom

🇬🇧

Stepping Hill Hospital, Stockport, United Kingdom

and more 169 locations

A Study of Lasmiditan in Healthy Chinese Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2019-09-09
Last Posted Date
2021-07-01
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
36
Registration Number
NCT04081324
Locations
🇨🇳

HuaShan Hospital Affiliated To Fudan University, Shanghai, Shanghai, China

A Study of Lasmiditan (LY573144) in Children Aged 6 to 17 With Migraine

Phase 1
Completed
Conditions
Interventions
First Posted Date
2019-06-17
Last Posted Date
2020-09-01
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
18
Registration Number
NCT03988088
Locations
🇯🇵

Clinical Research Hospital, Tokyo, Shinjuku-Ku, Tokyo, Japan

🇺🇸

Newport Beach Clinical Research Associates, Inc., Newport Beach, California, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

and more 7 locations

A Study Lasmiditan (LY573144) in a Single Migraine Attack in Japanese Participants With Migraine

Phase 2
Completed
Conditions
Interventions
First Posted Date
2019-05-24
Last Posted Date
2021-06-11
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
846
Registration Number
NCT03962738
Locations
🇯🇵

Osaka Saiseikai Nakatsu Hospital, Osaka, Japan

🇯🇵

Tominaga Hospital, Osaka, Japan

🇯🇵

Kohnan Hospital, Kobe, Hyogo, Japan

and more 31 locations

A Study of Lasmiditan (LY573144) Over Four Migraine Attacks

Phase 3
Completed
Conditions
Interventions
First Posted Date
2018-09-14
Last Posted Date
2022-07-29
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1633
Registration Number
NCT03670810
Locations
🇦🇹

KH der Barmherzigen Schwestern Linz BetriebsGesmbH, Linz, Oberösterreich, Austria

🇩🇪

Praxis für Neurologie und Psychiatrie, Essen, North Rhine-Westphalia, Germany

🇨🇳

Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, China

and more 133 locations

A Study of Lasmiditan in Healthy Japanese and Caucasian Participants

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-07-09
Last Posted Date
2019-11-29
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
27
Registration Number
NCT03579940
Locations
🇺🇸

Covance, Dallas, Texas, United States

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