Solanezumab

Generic Name
Solanezumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
955085-14-0
Unique Ingredient Identifier
5D6PWO0333
Background

Solanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial.

Associated Conditions
-
Associated Therapies
-

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation.

First Posted Date
2020-11-10
Last Posted Date
2022-09-22
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
194
Registration Number
NCT04623242
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of California San Diego Medical Center, La Jolla, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Washington University in St. Louis, Saint Louis, Missouri, United States

๐Ÿ‡บ๐Ÿ‡ธ

Columbia University, New York, New York, United States

and more 22 locations

A Study of Solanezumab (LY2062430) in Participants With Prodromal Alzheimer's Disease

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2016-05-03
Last Posted Date
2019-10-10
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
26
Registration Number
NCT02760602
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Banner Sun Health Research Institute, Sun City, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Center for Neurosciences, Tucson, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Arizona Health Sciences Center, Tucson, Arizona, United States

and more 100 locations

A Study of LY2599666 in Healthy Participants and Participants With Mild Cognitive Impairment or Alzheimer's Disease (AD)

First Posted Date
2015-11-25
Last Posted Date
2020-06-17
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
50
Registration Number
NCT02614131
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Parexel Early Phase Unit at Glendale, Glendale, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

CRI Lifetree, Marlton, New Jersey, United States

๐Ÿ‡บ๐Ÿ‡ธ

PRA Health Sciences, Salt Lake City, Utah, United States

and more 1 locations

Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss

Phase 3
Completed
Conditions
Interventions
First Posted Date
2013-12-11
Last Posted Date
2023-12-28
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1169
Registration Number
NCT02008357
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Pennsylvania Hospital, Philadelphia, Pennsylvania, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Kansas Hospital, Fairway, Kansas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Washington University School of Medicine, Saint Louis, Missouri, United States

and more 62 locations

Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2013-07-16
Last Posted Date
2019-10-09
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
2129
Registration Number
NCT01900665
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Neurology Center of North Orange County, Fullerton, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

PharmaSite Research Inc, Baltimore, Maryland, United States

๐Ÿ‡บ๐Ÿ‡ธ

Senior Clinical Trials, Inc., Laguna Hills, California, United States

and more 116 locations

Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001

First Posted Date
2013-01-03
Last Posted Date
2024-07-03
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
490
Registration Number
NCT01760005
Locations
๐Ÿ‡จ๐Ÿ‡ฆ

UBC Hospital, Vancouver, British Columbia, Canada

๐Ÿ‡บ๐Ÿ‡ธ

University of Washington, Seattle, Washington, United States

๐Ÿ‡ซ๐Ÿ‡ท

CHU de Rouen - Hรดpital Charles Nicolle, Rouen, Seine Maritime, France

and more 35 locations

A Biomarker Study of Solanezumab in Patients With and Without Alzheimer's

Phase 2
Completed
Conditions
Interventions
First Posted Date
2010-06-22
Last Posted Date
2012-09-25
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
55
Registration Number
NCT01148498
Locations
๐Ÿ‡บ๐Ÿ‡ธ

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., St. Louis, Missouri, United States

Continued Safety Monitoring of Solanezumab (LY2062430) in Alzheimer's Disease

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2010-05-21
Last Posted Date
2019-10-08
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1457
Registration Number
NCT01127633
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Camberwell, London, United Kingdom

Effect of LY2062430 on the Progression of Alzheimer's Disease

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-05-20
Last Posted Date
2012-09-25
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1000
Registration Number
NCT00905372
Locations
๐Ÿ‡ฏ๐Ÿ‡ต

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Tokyo, Japan

Effect of LY2062430 on the Progression of Alzheimer's Disease

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-05-20
Last Posted Date
2012-12-13
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
1040
Registration Number
NCT00904683
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Swindon, Wiltshire, United Kingdom

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