Omecamtiv Mecarbil
- Generic Name
- Omecamtiv Mecarbil
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C20H24FN5O3
- CAS Number
- 873697-71-3
- Unique Ingredient Identifier
- 2M19539ERK
- Background
Omecamtiv Mecarbil has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among others.
- Associated Conditions
- -
- Associated Therapies
- -
Omecamtiv Mecarbil Post-trial Access Study
- Conditions
- Interventions
- First Posted Date
- 2020-07-09
- Last Posted Date
- 2021-07-30
- Lead Sponsor
- Cytokinetics
- Registration Number
- NCT04464525
Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2018-11-30
- Last Posted Date
- 2023-03-07
- Lead Sponsor
- Cytokinetics
- Target Recruit Count
- 276
- Registration Number
- NCT03759392
- Locations
- πΊπΈ
Alaska Heart and Vascular Institute, Anchorage, Alaska, United States
πΊπΈGlacier View Research Institute, Cardiology, Kalispell, Montana, United States
π¨π¦Mcgill University Health Centre (MUHC)-The Montreal General Hospital (MGH), Montreal, Quebec, Canada
Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection Fraction
- Conditions
- Interventions
- First Posted Date
- 2016-10-11
- Last Posted Date
- 2021-11-05
- Lead Sponsor
- Cytokinetics
- Target Recruit Count
- 8256
- Registration Number
- NCT02929329
- Locations
- π¬π§
Research Site, Worcester, United Kingdom
Pharmacokinetics and Safety Study of Omecamtiv Mecarbil in Healthy Japanese Adults
- First Posted Date
- 2015-11-10
- Last Posted Date
- 2021-07-27
- Lead Sponsor
- Cytokinetics
- Target Recruit Count
- 50
- Registration Number
- NCT02601001
- Locations
- π―π΅
Research Site, Kagoshima-shi, Kagoshima, Japan
A Pharmacokinetic and Pharmacodynamic Study of Omecamtiv Mecarbil in Healthy Volunteers
- First Posted Date
- 2011-06-27
- Last Posted Date
- 2015-10-14
- Lead Sponsor
- Cytokinetics
- Target Recruit Count
- 35
- Registration Number
- NCT01380223
- Locations
- π¬π§
ICON Development Solutions, Manchester, England, United Kingdom
Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)
- First Posted Date
- 2011-02-21
- Last Posted Date
- 2021-07-27
- Lead Sponsor
- Cytokinetics
- Target Recruit Count
- 614
- Registration Number
- NCT01300013
- Locations
- π¬π§
Research Site, Harrow, United Kingdom
Pharmacokinetic Study of Omecamtiv Mecarbil in Heart Failure Patients
- First Posted Date
- 2010-02-26
- Last Posted Date
- 2021-07-30
- Lead Sponsor
- Cytokinetics
- Registration Number
- NCT01077167
Drug Development Updates
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