Uprosertib

Generic Name
Uprosertib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H16Cl2F2N4O2
CAS Number
1047634-65-0
Unique Ingredient Identifier
ZXM835LQ5E
Background

Uprosertib has been used in trials studying the treatment of Cancer, Melanoma, Solid Tumours, Cervical Cancer, and HER2/Neu Negative, among others.

Associated Conditions
-
Associated Therapies
-

Trametinib and Akt Inhibitor GSK2141795 in Treating Patients With Relapsed or Refractory Multiple Myeloma

First Posted Date
2013-11-21
Last Posted Date
2022-03-02
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
25
Registration Number
NCT01989598
Locations
πŸ‡¨πŸ‡¦

University Health Network-Princess Margaret Hospital, Toronto, Ontario, Canada

πŸ‡¨πŸ‡¦

Tom Baker Cancer Centre, Calgary, Alberta, Canada

πŸ‡¨πŸ‡¦

Cross Cancer Institute, Edmonton, Alberta, Canada

and more 2 locations

Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma

First Posted Date
2013-11-08
Last Posted Date
2020-02-24
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
42
Registration Number
NCT01979523
Locations
πŸ‡ΊπŸ‡Έ

M D Anderson Cancer Center, Houston, Texas, United States

πŸ‡«πŸ‡·

Institut Curie Paris, Paris, France

πŸ‡ΊπŸ‡Έ

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States

and more 4 locations

Trametinib With or Without GSK2141795 in Treating Patients With Recurrent or Persistent Endometrial Cancer

First Posted Date
2013-09-05
Last Posted Date
2020-10-14
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
26
Registration Number
NCT01935973
Locations
πŸ‡ΊπŸ‡Έ

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

πŸ‡ΊπŸ‡Έ

University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States

πŸ‡ΊπŸ‡Έ

Washington University School of Medicine, Saint Louis, Missouri, United States

and more 19 locations

Uprosertib, Dabrafenib, and Trametinib in Treating Patients With Stage IIIC-IV Cancer

First Posted Date
2013-07-18
Last Posted Date
2024-11-11
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
27
Registration Number
NCT01902173
Locations
πŸ‡ΊπŸ‡Έ

UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California, United States

πŸ‡ΊπŸ‡Έ

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

πŸ‡ΊπŸ‡Έ

Clackamas Radiation Oncology Center, Clackamas, Oregon, United States

and more 13 locations
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