CUDC-101

Generic Name
CUDC-101
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C24H26N4O4
CAS Number
1012054-59-9
Unique Ingredient Identifier
1A7Y9MP123
Background

CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.

Associated Conditions
-
Associated Therapies
-

Phase I Study to Assess the Safety, Tolerability, and Pharmacokinetics of Orally Administered CUDC-101 in Cancer Patients

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2012-10-08
Last Posted Date
2018-02-12
Lead Sponsor
Curis, Inc.
Target Recruit Count
3
Registration Number
NCT01702285
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Southern Texas Accelerated Research Therapeutics, San Antonio, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Karmanos Cancer Institute, Detroit, Michigan, United States

Phase I Study of CUDC-101 With Cisplatin and Radiation in Subjects With Head & Neck Cancer

Phase 1
Completed
Conditions
First Posted Date
2011-06-29
Last Posted Date
2018-02-22
Lead Sponsor
Curis, Inc.
Target Recruit Count
12
Registration Number
NCT01384799
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Vanderbilt University, Nashville, Tennessee, United States

๐Ÿ‡บ๐Ÿ‡ธ

Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States

๐Ÿ‡บ๐Ÿ‡ธ

Massachusetts General Hospital, Boston, Massachusetts, United States

and more 4 locations

A Phase Ib Expansion Study Investigating the Safety, Efficacy, and Pharmacokinetics of Intravenous CUDC-101 in Subjects With Advanced Head and Neck, Gastric, Breast, Liver and Non-small Cell Lung Cancer Tumors

First Posted Date
2010-07-29
Last Posted Date
2016-03-01
Lead Sponsor
Curis, Inc.
Target Recruit Count
47
Registration Number
NCT01171924
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Mary Crowley Cancer Research Centers, Dallas, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Mountain Blue Global Cancer Care, Wheat Ridge, Colorado, United States

๐Ÿ‡บ๐Ÿ‡ธ

San Diego Pacific Oncology and Hematology Associates, Encinitas, California, United States

and more 4 locations

A Phase I Study of the Safety, Pharmacokinetics, and Anti-Tumor Activity of CUDC-101 in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
First Posted Date
2008-08-06
Last Posted Date
2018-02-22
Lead Sponsor
Curis, Inc.
Target Recruit Count
25
Registration Number
NCT00728793
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Karmanos Cancer Institute, Detroit, Michigan, United States

๐Ÿ‡บ๐Ÿ‡ธ

START (South Texas Accelerated Research Therapeutics), San Antonio, Texas, United States

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