Nefopam

Generic Name
Nefopam
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C17H19NO
CAS Number
13669-70-0
Unique Ingredient Identifier
4UP8060B7J
Background

Nefopam is under investigation for the prevention of Cholecystitis and Post Anaesthetic Shivering. Nefopam has been investigated for the prevention of Kidney Transplantation.

Indication

用于术后镇痛、癌痛、急性外伤痛。亦可用于急性胃炎、胆道蛔虫症、输尿管结石等内脏平滑肌收缩绞痛;局部麻醉、针麻等麻醉辅助用药。

Associated Conditions
Pain
Associated Therapies
-

Efficacy of Intravenous Nefopam, Dexmedetomidine, and Meperidine in Preventing Post-Spinal Anesthesia Shivering in Adult Patients Undergoing Lower Abdominal and Lower Limb Surgeries.

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-10-04
Last Posted Date
2024-10-04
Lead Sponsor
Kasr El Aini Hospital
Target Recruit Count
240
Registration Number
NCT06627816
Locations
🇪🇬

Kasr Al Aini Hospitals, Cairo, Egypt

Early and Late Effects of Nefopam in Multimodal Analgesia After Total Hip Arthroplasty (NEFARTHRO)

Phase 3
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-04-05
Last Posted Date
2024-04-05
Lead Sponsor
University Hospital, Tours
Target Recruit Count
546
Registration Number
NCT06349798
Locations
🇫🇷

Anaesthesia - Intensive care, Poitiers, France

🇫🇷

Anesthesia - intensive care, Tours, France

Nefopam as a Multimodal Analgesia for Thoracic Surgery

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2021-12-29
Last Posted Date
2023-02-14
Lead Sponsor
Kangbuk Samsung Hospital
Target Recruit Count
46
Registration Number
NCT05173337
Locations
🇰🇷

Eunah Cho, Seoul, Korea, Republic of

Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study

First Posted Date
2021-10-08
Last Posted Date
2023-02-08
Lead Sponsor
Cairo University
Target Recruit Count
60
Registration Number
NCT05071352
Locations
🇪🇬

Cairo University Hospitals (Kasr Alainy), Cairo, Egypt

Safety, Tolerability and Efficacy of Nefopam Cream in Burn Patients

First Posted Date
2020-12-28
Last Posted Date
2024-01-18
Lead Sponsor
University of Alberta
Target Recruit Count
60
Registration Number
NCT04685577
Locations
🇨🇦

University of Alberta Hospital, Edmonton, Alberta, Canada

Interest of the Nefopam and PCA Morphine Combination for Postoperative Analgesia in Patients Undergoing Colon Surgery

First Posted Date
2018-08-08
Last Posted Date
2018-08-08
Lead Sponsor
Centre Hospitalier Universitaire de Nīmes
Target Recruit Count
80
Registration Number
NCT03619538

Effectiveness of Nefopam in Breast Cancer Surgery

First Posted Date
2016-10-31
Last Posted Date
2018-01-11
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
88
Registration Number
NCT02949310
Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of

Nefopam/Fentanyl Postoperative Intravenous Patient-Controlled-Analgesia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-11-04
Last Posted Date
2015-11-05
Lead Sponsor
Seoul National University Hospital
Target Recruit Count
73
Registration Number
NCT02596269

Combination Effect of Nefopam With Propacetamol for Postoperative Pain After Thyroidectomy

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2015-10-16
Last Posted Date
2019-03-21
Lead Sponsor
Yonsei University
Target Recruit Count
84
Registration Number
NCT02577068
Locations
🇰🇷

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of

Postoperative Analgesic Effect of Nefopam

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2015-09-28
Last Posted Date
2016-10-28
Lead Sponsor
Seoul National University Bundang Hospital
Target Recruit Count
78
Registration Number
NCT02561494
Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam, Gyeonggi, Korea, Republic of

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