1,2-Benzodiazepine

The DOJ filed a civil complaint against CVS Pharmacy Inc., accusing it of unlawfully filling prescriptions for highly addictive opioids, violating federal health care laws, and seeking reimbursement from federal health care programs, violating the False Claims Act. CVS denies the allegations, stating it has cooperated with the DOJ’s investigation for over four years and that all prescriptions were FDA-approved and written by licensed practitioners.

A study warns doctors may be overprescribing benzodiazepines like Xanax and Valium to stroke survivors, often for longer than a week, potentially hindering recovery and increasing addiction risk. Researchers analyzed Medicare claims data from over 120,000 stroke victims aged 65 and older, finding 5% were prescribed benzodiazepines within 90 days of their stroke, with 75% of prescriptions lasting over seven days. The American Geriatrics Society advises avoiding benzodiazepines in older adults due to risks like cognitive impairment and falls.

Imaging revealed the brain's glymphatic system's waste clearance. Apitegromab improved motor function in spinal muscular atrophy. Masked tapering helped older adults discontinue benzodiazepine receptor agonists. Allogeneic virus-specific T cells may benefit progressive multifocal leukoencephalopathy. The BBC explored microglia, and Nature mapped fruit fly brain neurons. Brainstem changes from inflammation were seen in COVID-19 patients. Identifying SOD1 gene variants is a barrier to tofersen treatment in ALS. Lessons from multiple sclerosis could guide Parkinson's disease research. Dalzanemdor failed to improve cognition in Alzheimer's disease.