Azeliragon

Generic Name
Azeliragon
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C32H38ClN3O2
CAS Number
603148-36-3
Unique Ingredient Identifier
LPU25F15UQ
Background

Azeliragon has been used in trials studying the treatment of Alzheimer's Disease.

Associated Conditions
-
Associated Therapies
-

Concurrent Azeliragon With Craniospinal Irradiation

First Posted Date
2024-12-09
Last Posted Date
2024-12-09
Lead Sponsor
NYU Langone Health
Target Recruit Count
32
Registration Number
NCT06724926
Locations
πŸ‡ΊπŸ‡Έ

NYU Langone Health, New York, New York, United States

Azeliragon in MGMT Unmethylated Glioblastoma

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-08-14
Last Posted Date
2024-08-20
Lead Sponsor
Cantex Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT05986851
Locations
πŸ‡ΊπŸ‡Έ

University of Washington, Seattle, Washington, United States

πŸ‡ΊπŸ‡Έ

Miami Cancer Institute - Baptist Health, Miami, Florida, United States

πŸ‡ΊπŸ‡Έ

The University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, United States

and more 5 locations

A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study to Determine the Safety and Effectiveness of Azeliragon in the Treatment of Patients Hospitalized for Coronavirus Disease 2019 (COVID-19) or Pneumonia

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-04-18
Last Posted Date
2023-10-31
Lead Sponsor
Salim S. Hayek
Target Recruit Count
144
Registration Number
NCT05815485
Locations
πŸ‡ΊπŸ‡Έ

University of Michigan, Ann Arbor, Michigan, United States

πŸ‡ΊπŸ‡Έ

Rush University, Chicago, Illinois, United States

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

First Posted Date
2023-03-29
Last Posted Date
2024-10-01
Lead Sponsor
Baptist Health South Florida
Target Recruit Count
46
Registration Number
NCT05789589
Locations
πŸ‡ΊπŸ‡Έ

Miami Cancer Institute at Baptist Health, Inc., Miami, Florida, United States

Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients With Glioblastoma

First Posted Date
2023-03-17
Last Posted Date
2024-04-25
Lead Sponsor
City of Hope Medical Center
Target Recruit Count
21
Registration Number
NCT05773664
Locations
πŸ‡ΊπŸ‡Έ

City of Hope Medical Center, Duarte, California, United States

Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancer

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2023-03-13
Last Posted Date
2024-06-14
Lead Sponsor
Cantex Pharmaceuticals
Target Recruit Count
30
Registration Number
NCT05766748
Locations
πŸ‡ΊπŸ‡Έ

Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California, United States

πŸ‡ΊπŸ‡Έ

Prisma Health - Upstate, Greenville, South Carolina, United States

πŸ‡ΊπŸ‡Έ

Williamette Valley Cancer Institute and Research Center, Eugene, Oregon, United States

and more 3 locations

Study of Azeliragon in Patients With Mild Alzheimer's Disease and Impaired Glucose Tolerance

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2019-06-10
Last Posted Date
2022-01-21
Lead Sponsor
vTv Therapeutics
Target Recruit Count
43
Registration Number
NCT03980730
Locations
πŸ‡ΊπŸ‡Έ

NeuroStudies.net LLC, Decatur, Georgia, United States

πŸ‡¨πŸ‡¦

Q&T Research Sherbrooke Inc, Sherbrooke, Quebec, Canada

πŸ‡ΊπŸ‡Έ

Tucson Neuroscience Research, Tucson, Arizona, United States

and more 28 locations

Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2014-03-06
Last Posted Date
2021-05-07
Lead Sponsor
vTv Therapeutics
Target Recruit Count
880
Registration Number
NCT02080364
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