Radium Ra-223

Generic Name
Radium Ra-223
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
Ra
CAS Number
15623-45-7
Unique Ingredient Identifier
8BR2SOL3L1
Background

Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC).

Associated Conditions
-
Associated Therapies
-

Efficacy of Ra-223 in PSMA PET Optimally Selected Patients

First Posted Date
2023-06-29
Last Posted Date
2024-11-25
Lead Sponsor
University of California, San Francisco
Target Recruit Count
54
Registration Number
NCT05924672
Locations
🇺🇸

University of California, San Francisco, San Francisco, California, United States

Darolutamide With Radium-223 or Placebo and the Effect on Radiological Progression-Free Survival for Patients With mCSPC

First Posted Date
2023-03-16
Last Posted Date
2023-09-14
Lead Sponsor
GenesisCare USA
Registration Number
NCT05771896

Combination of Radium-223 and Lutetium-177 PSMA-I&T in Men With Metastatic Castration-Resistant Prostate Cancer

First Posted Date
2022-05-19
Last Posted Date
2023-10-27
Lead Sponsor
Peter MacCallum Cancer Centre, Australia
Target Recruit Count
36
Registration Number
NCT05383079
Locations
🇦🇺

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

Health-related Quality of Life, Psychological Distress and Fatigue in Metastatic CRPC Patients Treated With Radium-223

First Posted Date
2021-08-09
Last Posted Date
2021-08-09
Lead Sponsor
Radboud University Medical Center
Target Recruit Count
122
Registration Number
NCT04995614
Locations
🇳🇱

Catharina ziekenhuis, Eindhoven, Netherlands

🇳🇱

Canisius-Wilhelmina ziekenhuis, Nijmegen, Netherlands

🇳🇱

Rijnstate ziekenhuis, Arnhem, Netherlands

and more 8 locations

Radium-223 in Biochemically Recurrent Prostate Cancer

First Posted Date
2019-12-20
Last Posted Date
2024-12-06
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
26
Registration Number
NCT04206319
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

RAdium-223 and SABR Versus SABR for Oligometastatic Prostate Cancers

First Posted Date
2019-07-30
Last Posted Date
2024-11-04
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
64
Registration Number
NCT04037358
Locations
🇺🇸

Johns Hopkins, Baltimore, Maryland, United States

A Study to Test Radium-223 With Docetaxel in Patients With Prostate Cancer

First Posted Date
2018-07-02
Last Posted Date
2024-11-22
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
738
Registration Number
NCT03574571
Locations
🇺🇸

Millennium Physicians, Houston, Texas, United States

🇪🇸

Vall d'Hebron Institute of Oncology (VHIO) (Data Collection Only), Barcelona, Spain

🇪🇸

Clinic de Barcelona, Barcelona, Spain

and more 68 locations

Sequencing of Radium-223 and Docetaxel in Symptomatic Bone-only Metastatic Castration-resistant Prostate Cancer

First Posted Date
2017-07-26
Last Posted Date
2023-05-30
Lead Sponsor
Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori
Target Recruit Count
70
Registration Number
NCT03230734
Locations
🇮🇹

U.O. Oncologia PO Vito Fazzi, Lecce, LE, Italy

🇮🇹

UO Oncologia Medica, IRST IRCCS, Meldola, FC, Italy

🇮🇹

IRCCS Istituto Clinico Humanitas, Rozzano, Milano, Italy

and more 12 locations

Radium-223 and Atezolizumab in Patients With Urothelial Carcinoma With Bone Metastases Who Have Had Disease Progression After Platinum-Based Chemotherapy

Early Phase 1
Terminated
Conditions
Interventions
First Posted Date
2017-07-05
Last Posted Date
2018-10-24
Lead Sponsor
University of Michigan Rogel Cancer Center
Target Recruit Count
1
Registration Number
NCT03208712
Locations
🇺🇸

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

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