Radium Ra-223

Generic Name
Radium Ra-223
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
Ra
CAS Number
15623-45-7
Unique Ingredient Identifier
8BR2SOL3L1
Background

Radium 223 is under investigation in clinical trial NCT02463799 (Ph 2 Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC).

Associated Conditions
-
Associated Therapies
-

Study Evaluating the Addition of Pembrolizumab to Radium-223 in mCRPC

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2017-03-28
Last Posted Date
2024-11-21
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
45
Registration Number
NCT03093428
Locations
🇺🇸

Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

Trial of Rad-223 Activity in Asymptomatic Patients With mCRPC While on Abiraterone or Enzalutamide Besides AR-V7 Status

Phase 2
Completed
Conditions
Interventions
First Posted Date
2016-12-23
Last Posted Date
2024-12-11
Lead Sponsor
MedSIR
Target Recruit Count
52
Registration Number
NCT03002220
Locations
🇪🇸

MedSIR Investigative site, Madrid, Spain

🇪🇸

MedSIR investigative site, Palma De Mallorca, Spain

Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-06-04
Last Posted Date
2021-07-08
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
36
Registration Number
NCT02463799
Locations
🇺🇸

Sibley Memorial Hospital, Washington, District of Columbia, United States

🇺🇸

Tulane Cancer Center, New Orleans, Louisiana, United States

🇺🇸

Cedars-Sinai Medical Center, Los Angeles, California, United States

and more 2 locations

Exploratory Study of Radium-223 and VEGF-Targeted Therapy in Patients With Metastatic Renal Cell Carcinoma and Bone Mets

First Posted Date
2015-04-02
Last Posted Date
2020-03-04
Lead Sponsor
Dana-Farber Cancer Institute
Target Recruit Count
30
Registration Number
NCT02406521
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

Non-Randomized Trial Assessing Pain Efficacy With Radium-223 in Symptomatic Metastatic Castration-Resistant Prostate Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2014-10-29
Last Posted Date
2023-04-07
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
29
Registration Number
NCT02278055
Locations
🇺🇸

New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, New York, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

🇺🇸

University of North Carolina, Chapel Hill, North Carolina, United States

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