5-fluoro-2'-deoxycytidine

Generic Name: 5-fluoro-2'-deoxycytidine

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₉H_₁₂FN_₃O_₄

CAS Number: 10356-76-0

Unique Ingredient Identifier: KUA4693H5W

Background: 5-fluoro-2'-deoxycytidine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, and Urinary Bladder Neoplasms, among others.

Associated Conditions: -

Associated Therapies: -

Clinical Trials

5-Fluoro-2'-Deoxycytidine and Tetrahydrouridine in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

Phase 1

Completed

Conditions: Adult Acute Myeloid Leukemia
Secondary Acute Myeloid Leukemia
Untreated Adult Acute Myeloid Leukemia
de Novo Myelodysplastic Syndromes
Previously Treated Myelodysplastic Syndromes
Recurrent Adult Acute Myeloid Leukemia
Secondary Myelodysplastic Syndromes

Interventions: Drug: 5-fluoro-2-deoxycytidine
Drug: tetrahydrouridine
Other: laboratory biomarker analysis
Genetic: reverse transcriptase-polymerase chain reaction
Genetic: DNA methylation analysis

First Posted Date: 2009-12-31

Last Posted Date: 2015-06-08

Lead Sponsor: City of Hope Medical Center

Target Recruit Count: 25

Registration Number: NCT01041443

Locations: 🇺🇸
City of Hope, Duarte, California, United States

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