Tenofovir
- Generic Name
- Tenofovir
- Brand Names
- Vemlidy, Tenofovir disoproxil Zentiva
- Drug Type
- Small Molecule
- Chemical Formula
- C9H14N5O4P
- CAS Number
- 147127-20-6
- Unique Ingredient Identifier
- W4HFE001U5
- Background
Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and this agent was commercially available since 2008 in ...
- Indication
Tenofovir has been shown to be effective against HIV, herpes simplex virus-2, and hepatitis B virus.
To know more about the specific product indications, please visit the information in the orally available forms of tenofovir, tenofovir alafenamide and tenofovir disoproxil.
- Associated Conditions
- -
- Associated Therapies
- -
Tenofovir Antiviral Therapy Following Transarterial Chemoembolization for HBV Related Hepatocellular Carcinoma
- Conditions
- Interventions
- First Posted Date
- 2013-06-07
- Last Posted Date
- 2014-09-04
- Lead Sponsor
- Taichung Veterans General Hospital
- Target Recruit Count
- 320
- Registration Number
- NCT01872988
- Locations
- 🇨🇳
Chia-Yi Christine Hospital, Chia-Yi, Taiwan
🇨🇳Taichung Veterans General Hospital, Taichung, Taiwan
🇨🇳Mackay Memorial Hosp, Taipei, Taiwan
Tenofovir Versus Lamivudine for Patients of Chronic Hepatitis B With Severe Acute Exacerbation
- First Posted Date
- 2013-05-07
- Last Posted Date
- 2014-09-16
- Lead Sponsor
- Kaohsiung Veterans General Hospital.
- Target Recruit Count
- 120
- Registration Number
- NCT01848743
- Locations
- 🇨🇳
Kaohsiung Veterans General Hospigal, Kaohsiung, Taiwan
🇨🇳Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
Study to Evaluate a HIV Drug for the Treatment of HIV Infection
- First Posted Date
- 2013-03-04
- Last Posted Date
- 2019-11-25
- Lead Sponsor
- ViiV Healthcare
- Target Recruit Count
- 107
- Registration Number
- NCT01803074
- Locations
- 🇩🇪
GSK Investigational Site, Berlin, Germany
TDF VS LAM + ADV in LAM + ADV Treated LAM-resistant CHB Patients With Undetectable Hepatitis B Virus DNA
- Conditions
- Interventions
- First Posted Date
- 2012-11-22
- Last Posted Date
- 2016-10-28
- Lead Sponsor
- Keimyung University Dongsan Medical Center
- Target Recruit Count
- 171
- Registration Number
- NCT01732367
- Locations
- 🇰🇷
Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea, Republic of
To Compare the Efficacy of Combined Tenofovir Plus Telbivudine vs Tenofovir Alone in Patients With Spontaneous Reactivation of Hepatitis B
- Conditions
- Interventions
- First Posted Date
- 2012-11-22
- Last Posted Date
- 2016-03-23
- Lead Sponsor
- Institute of Liver and Biliary Sciences, India
- Target Recruit Count
- 69
- Registration Number
- NCT01732224
- Locations
- 🇮🇳
Institute of Liver & Biliary Sciences (ILBS), New Delhi, Delhi, India
A Study to Compare Efficacy and Safety of Tenofovir Used Alone or in Combination With Pegylated Interferon Alpha-2b in Participants With Chronic Hepatitis B and Elevated Alanine Aminotransferase (MK-4031-384)
- Conditions
- Interventions
- First Posted Date
- 2012-11-15
- Last Posted Date
- 2013-09-19
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Registration Number
- NCT01727271
Tenofovir Disoproxil Fumarate vs. Entecavir in Chronic Hepatitis B Patients With Partial Virologic Response to Entecavir
- First Posted Date
- 2012-10-22
- Last Posted Date
- 2016-11-09
- Lead Sponsor
- Korea University
- Target Recruit Count
- 60
- Registration Number
- NCT01711567
- Locations
- 🇰🇷
Korea University Ansan Hospital, Ansan, Gyeonggi-do, Korea, Republic of
Economic, Clinical and Quality of Life Assessment in Patients on Antiretroviral Therapy
- First Posted Date
- 2012-09-26
- Last Posted Date
- 2014-11-24
- Lead Sponsor
- Tufts University
- Target Recruit Count
- 68
- Registration Number
- NCT01694017
- Locations
- 🇮🇳
Christian Medical College, Vellore, Tamilnadu, India
Tenofovir vs. Tenofovir Plus Entecavir in Entecavir-Resistant Chronic Hepatitis B
- Conditions
- Interventions
- First Posted Date
- 2012-07-12
- Last Posted Date
- 2018-05-09
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 88
- Registration Number
- NCT01639092
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
Tenofovir Plus Entecavir vs. Tenofovir in Adefovir-Resistant Chronic Hepatitis B
- Conditions
- Interventions
- First Posted Date
- 2012-07-12
- Last Posted Date
- 2018-02-20
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 102
- Registration Number
- NCT01639066
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.