Emtricitabine
- Generic Name
- Emtricitabine
- Brand Names
- Atripla, Biktarvy, Complera, Descovy, Emtriva, Genvoya, Odefsey, Stribild, Truvada
- Drug Type
- Small Molecule
- Chemical Formula
- C8H10FN3O3S
- CAS Number
- 143491-57-0
- Unique Ingredient Identifier
- G70B4ETF4S
- Background
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of ...
- Indication
Emtricitabine is indicated in combination with other medications for the treatment of HIV-1 infections; treatment of HIV-1 infections in pediatric patients 25-35kg, treatment of HIV-1 infections in adult patients ≥35kg, for pre exposure prophylaxis of HIV-1 in adolescent and adult patients excluding those who have receptive vaginal sex; treatment of HIV-1 in...
- Associated Conditions
- HIV Transmission, Human Immunodeficiency Virus (HIV) Infections, Human Immunodeficiency Virus Type 1 (HIV-1) Infection
- Associated Therapies
- Pre-Exposure Prophylaxis (PrEP)
A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy
- Conditions
- Interventions
- First Posted Date
- 2023-08-07
- Last Posted Date
- 2024-08-19
- Lead Sponsor
- ViiV Healthcare
- Target Recruit Count
- 412
- Registration Number
- NCT05979311
- Locations
- 🇬🇧
GSK Investigational Site, London, United Kingdom
Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana
- First Posted Date
- 2021-04-28
- Last Posted Date
- 2024-02-29
- Lead Sponsor
- Duke University
- Target Recruit Count
- 200
- Registration Number
- NCT04862975
- Locations
- 🇿🇦
Botswana-UPenn Partnership, Botswana, Gaborone, South Africa
🇿🇦Old Naledi Clinic, Botswana, Gaborone, South Africa
🇿🇦Mogoditshane Clinic KDC, Botswana, Gaborone, South Africa
Evaluation of Drug Interaction Between HS-10234 and Emtriccitabine
- First Posted Date
- 2020-07-20
- Last Posted Date
- 2020-10-01
- Lead Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
- Target Recruit Count
- 36
- Registration Number
- NCT04477096
- Locations
- 🇨🇳
Xiangya Hospital, Central South University, Changsha, Hunan, China
Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract
- Conditions
- First Posted Date
- 2017-07-14
- Last Posted Date
- 2024-04-16
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 28
- Registration Number
- NCT03218085
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
PK and PD Study of Oral F/TAF for HIV Prevention
- Conditions
- Interventions
- First Posted Date
- 2016-09-19
- Last Posted Date
- 2018-02-19
- Lead Sponsor
- CONRAD
- Target Recruit Count
- 73
- Registration Number
- NCT02904369
- Locations
- 🇺🇸
Eastern Virginia Medical School Clinical Research Center, Norfolk, Virginia, United States
🇺🇸Magee-Womens Research Institute and Foundation, Pittsburgh, Pennsylvania, United States
🇩🇴Profamilia, Santo Domingo, Dominican Republic
Efficacy of VHM After Treatment Interruption in Subjects Initiating ART During Acute HIV Infection
- Conditions
- Interventions
- First Posted Date
- 2015-06-19
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- SEARCH Research Foundation
- Target Recruit Count
- 15
- Registration Number
- NCT02475915
- Locations
- 🇹🇭
SEARCH, the Thai Red Cross AIDS Research Centre, Bangkok, Thailand
Emtricitabine for Naive Chinese Chronic Hepatitis B Patients
- First Posted Date
- 2014-12-30
- Last Posted Date
- 2014-12-30
- Lead Sponsor
- Asian-Pacific Alliance of Liver Disease, Beijing
- Target Recruit Count
- 2000
- Registration Number
- NCT02327663
Emtricitabine for Prevention of Vertical Transmission of HBV in Chinese Pregnant HBsAg Positive Patients
- First Posted Date
- 2014-12-30
- Last Posted Date
- 2014-12-30
- Lead Sponsor
- Asian-Pacific Alliance of Liver Disease, Beijing
- Target Recruit Count
- 200
- Registration Number
- NCT02327715
Emtricitabine for Naive Chinese Pregnant Chronic Hepatitis B Patients
- First Posted Date
- 2014-12-30
- Last Posted Date
- 2014-12-30
- Lead Sponsor
- Asian-Pacific Alliance of Liver Disease, Beijing
- Target Recruit Count
- 200
- Registration Number
- NCT02327702
Emtricitabine for Naive Child Chinese Chronic Hepatitis B Patients
- First Posted Date
- 2014-12-30
- Last Posted Date
- 2014-12-30
- Lead Sponsor
- Asian-Pacific Alliance of Liver Disease, Beijing
- Target Recruit Count
- 200
- Registration Number
- NCT02327676
Drug Development Updates
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