Methylprednisolone hemisuccinate

Generic Name
Methylprednisolone hemisuccinate
Brand Names
Solu-medrol
Drug Type
Small Molecule
Chemical Formula
C26H34O8
CAS Number
2921-57-5
Unique Ingredient Identifier
5GMR90S4KN
Background

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.

Associated Conditions
Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
Associated Therapies
Palliative Treatment
Clinical Trials
Related News

Methylprednisolone Before Fludeoxyglucose-Labeled Positron Emission Tomography in Patients With Lung Cancer

First Posted Date
2013-02-12
Last Posted Date
2018-06-28
Lead Sponsor
Ohio State University Comprehensive Cancer Center
Registration Number
NCT01789892

Efficacy and Safety of MEthylprednisolone Administered Intravenously for the Treatment of Patients With Active AnkyLosing spondyLitis (METALL)

First Posted Date
2013-02-12
Last Posted Date
2013-02-12
Lead Sponsor
Saratov State Medical University
Target Recruit Count
20
Registration Number
NCT01790022
Locations
🇷🇺

Department of Rheumatology, Saratov Region Hospital, Saratov, Russian Federation

Effect of Steroids on Cerebral Inflammation and Neuronal Damage After Surgical Aortic Valve Replacement

Not Applicable
Completed
Conditions
Aortic Stenosis
Interventions
Drug: Methylprednisolone
Drug: Placebo
First Posted Date
2012-12-24
Last Posted Date
2017-06-01
Lead Sponsor
Sahlgrenska University Hospital, Sweden
Target Recruit Count
30
Registration Number
NCT01755338
Locations
🇸🇪

Sahlgrenska University Hospital, Göteborg, VGR, Sweden

Methylprednisolone N Acetylcysteine in Hepatic Resections

First Posted Date
2012-11-15
Last Posted Date
2013-11-13
Lead Sponsor
Istituto Clinico Humanitas
Target Recruit Count
50
Registration Number
NCT01726465
Locations
🇮🇹

Istituto Clinico Humanitas IRCCS, Rozzano, Milano, Italy

CHOP vs GEM-P in 1st Line Treatment of T-cell Lymphoma, Multicentre Phase II Study

First Posted Date
2012-11-01
Last Posted Date
2018-03-15
Lead Sponsor
Royal Marsden NHS Foundation Trust
Target Recruit Count
87
Registration Number
NCT01719835
Locations
🇬🇧

Royal Marsden NHS Foundation Trust - London and Surrey, London, United Kingdom

Alternative Treatment Paradigm for Natalizumab Trial

Phase 2
Withdrawn
Conditions
Multiple Sclerosis (MS)
Interventions
Drug: methylprednisolone
First Posted Date
2012-10-19
Last Posted Date
2016-12-29
Lead Sponsor
University of Texas Southwestern Medical Center
Registration Number
NCT01710228
Locations
🇺🇸

UT Southwestern Medical Center, Dallas, Texas, United States

A Proof of Concept Study to Determine the Local Delivery and Efficacy of Nanocort

First Posted Date
2012-07-23
Last Posted Date
2012-07-23
Lead Sponsor
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Target Recruit Count
21
Registration Number
NCT01647685
Locations
🇳🇱

AMC, Amsterdam, Netherlands

Efficacy of Short-term Immunosuppressive Therapy and Anti-allergenic Therapy in Severe Acute Exacerbation of Chronic Hepatitis B

First Posted Date
2012-06-25
Last Posted Date
2013-10-10
Lead Sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
120
Registration Number
NCT01627236
Locations
🇨🇳

Deparment of Infectious Diseases, the Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

First Posted Date
2012-06-21
Last Posted Date
2024-11-28
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
140
Registration Number
NCT01624805
Locations
🇺🇸

M D Anderson Cancer Center, Houston, Texas, United States

Effect of Dexamethasone and Methylprednisolone on Pain, Swelling and Trismus After Third Molar Surgery

Not Applicable
Completed
Conditions
Pain,
Edema,
Trismus
Interventions
Drug: Dexamethasone
Drug: Methylprednisolone
First Posted Date
2012-05-23
Last Posted Date
2012-05-23
Lead Sponsor
Federal University of the Valleys of Jequitinhonha and Mucuri
Target Recruit Count
18
Registration Number
NCT01603498
Locations
🇧🇷

Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, Minas Gerais, Brazil

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