Methylprednisolone hemisuccinate
- Generic Name
- Methylprednisolone hemisuccinate
- Brand Names
- Solu-medrol
- Drug Type
- Small Molecule
- Chemical Formula
- C26H34O8
- CAS Number
- 2921-57-5
- Unique Ingredient Identifier
- 5GMR90S4KN
- Background
A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
- Associated Conditions
- Acute Gouty Arthritis, Ankylosing Spondylitis (AS), Berylliosis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatitis bullous, Dermatomyositis (DM), Edema of the cerebrum, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Leukemias, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Pemphigus, Polymyositis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Refractory Uveitis, Regional Enteritis, Rheumatoid Arthritis, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute rheumatic carditis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Allergic Reactions, Symptomatic Sarcoidosis
- Associated Therapies
- Palliative Treatment
Phase I Study of High-Dose Cyclophosphamide and Total Body Irradiation With T Lymphocyte-Depleted Autologous Peripheral Blood Stem Cell or Bone Marrow Rescue in Patients With Multiple Sclerosis
Phase 1
Completed
- Conditions
- First Posted Date
- 2001-06-06
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Northwestern Memorial Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT00017628
- Locations
- ๐บ๐ธ
Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, United States
๐บ๐ธNorthwestern Memorial Hospital, Chicago, Illinois, United States
Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia
Not Applicable
- Conditions
- First Posted Date
- 2001-06-06
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Northwestern Memorial Hospital
- Target Recruit Count
- 3
- Registration Number
- NCT00017654
- Locations
- ๐บ๐ธ
Northwestern Memorial Hospital, Chicago, Illinois, United States
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases
- First Posted Date
- 2000-07-06
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- Fairview University Medical Center
- Target Recruit Count
- 10
- Registration Number
- NCT00006055
- Locations
- ๐บ๐ธ
Fairview University Medical Center, Minneapolis, Minnesota, United States
Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
Not Applicable
Terminated
- Conditions
- Immunologic Deficiency SyndromesChediak-Higashi SyndromeCommon Variable ImmunodeficiencyGraft Versus Host DiseaseX-Linked Lymphoproliferative SyndromeFamilial Erythrophagocytic LymphohistiocytosisHemophagocytic LymphohistiocytosisX-linked AgammaglobulinemiaWiskott-Aldrich SyndromeChronic Granulomatous Disease
- First Posted Date
- 2000-07-06
- Last Posted Date
- 2009-10-15
- Lead Sponsor
- Fairview University Medical Center
- Registration Number
- NCT00006054
- Locations
- ๐บ๐ธ
Fairview University Medical Center, Minneapolis, Minnesota, United States
Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia
Phase 1
Completed
- Conditions
- First Posted Date
- 2000-06-05
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 30
- Registration Number
- NCT00005898
- Locations
- ๐บ๐ธ
University of Minnesota Cancer Center, Minneapolis, Minnesota, United States
Phase III Randomized, Double-Blind Study of Dexamethasone Vs Dexamethasone/Methylprednisolone Vs Placebo for Bronchopulmonary Dysplasia
Phase 3
Completed
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 54
- Registration Number
- NCT00004785
Methylprednisolone Given by 24-Hour or 48-Hour Infusion Versus Tirilazad for Acute Spinal Cord Injury
Phase 3
Completed
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2008-09-10
- Target Recruit Count
- 497
- Registration Number
- NCT00004759
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
Phase 3
Completed
- Conditions
- Locations
- ๐บ๐ธ
Baystate Medical Center, Springfield, Massachusetts, United States
๐บ๐ธDuke University, Durham, North Carolina, United States
๐บ๐ธWake Forest University, Winston-Salem, North Carolina, United States
Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia
Phase 2
Completed
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Target Recruit Count
- 10
- Registration Number
- NCT00004323
- Locations
- ๐บ๐ธ
Center for Health Sciences, Los Angeles, California, United States
Phase II Randomized Study of Muromonab-CD3, Cyclosporine, Methylprednisolone, and Prednisone in Patients With Giant Cell Myocarditis
Phase 2
Completed
- Conditions
- First Posted Date
- 1999-10-19
- Last Posted Date
- 2010-09-09
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 40
- Registration Number
- NCT00004482
- Locations
- ๐บ๐ธ
Mayo Clinic, Rochester, Minnesota, United States
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