Cavosonstat

Generic Name
Cavosonstat
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C16H10ClNO3
CAS Number
1371587-51-7
Unique Ingredient Identifier
O2Z8Q22ZE4
Background

Cavosonstat is under investigation in clinical trial NCT02589236 (Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation).

Associated Conditions
-
Associated Therapies
-

PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study

First Posted Date
2019-10-17
Last Posted Date
2024-07-11
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
395
Registration Number
NCT04129931
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Cleveland Clinic, Cleveland, Ohio, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of California San Diego: Airway Research & Clinical Trials Center, San Diego, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of California San Francisco, San Francisco, California, United States

and more 26 locations

MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Cavosonstat (N91115) in Healthy Subjects (SNO-9)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-10-14
Last Posted Date
2017-01-31
Lead Sponsor
Nivalis Therapeutics, Inc.
Target Recruit Count
32
Registration Number
NCT02934139
Locations
๐Ÿ‡บ๐Ÿ‡ธ

DaVita Clinical Research, Lakewood, Colorado, United States

Study of Cavosonstat (N91115) in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor

Phase 2
Conditions
Interventions
First Posted Date
2016-03-31
Last Posted Date
2016-11-21
Lead Sponsor
Nivalis Therapeutics, Inc.
Target Recruit Count
19
Registration Number
NCT02724527
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Rainbow Babies and Children's Hospital - Case Medical Center, Cleveland, Ohio, United States

๐Ÿ‡บ๐Ÿ‡ธ

Nationwide Children's Hospital, Columbus, Ohio, United States

๐Ÿ‡บ๐Ÿ‡ธ

Johns Hopkins Hospital, Baltimore, Maryland, United States

and more 9 locations

Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation

Phase 2
Completed
Conditions
Interventions
First Posted Date
2015-10-28
Last Posted Date
2017-01-10
Lead Sponsor
Nivalis Therapeutics, Inc.
Target Recruit Count
138
Registration Number
NCT02589236
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Yale University, New Haven, Connecticut, United States

๐Ÿ‡บ๐Ÿ‡ธ

Maine Medical Center, Portland, Maine, United States

๐Ÿ‡บ๐Ÿ‡ธ

Johns Hopkins Hospital, Baltimore, Maryland, United States

and more 43 locations
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