Avexitide

Generic Name
Avexitide
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C149H234N40O47S
CAS Number
133514-43-9
Unique Ingredient Identifier
5313W10MYT
Background

Avexitide is under investigation in clinical trial NCT02996812 (Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia).

Associated Conditions
-
Associated Therapies
-

Avexitide Safety and Efficacy to Treat Acquired Hyperinsulinemic Hypoglycemia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2020-12-03
Last Posted Date
2023-06-09
Lead Sponsor
Dr. Tracey McLaughlin, MD
Target Recruit Count
25
Registration Number
NCT04652479
Locations
🇺🇸

Clinical and Translational Research Unit, Palo Alto, California, United States

The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D

First Posted Date
2017-08-11
Last Posted Date
2018-07-09
Lead Sponsor
University Hospital, Gentofte, Copenhagen
Target Recruit Count
15
Registration Number
NCT03246451
Locations
🇩🇰

Center for Diabetes Research, Gentofte, Copenhagen, Denmark

Delineation of the Role of Glucagon-like Peptide-1 Signalling in Relation to Increased Carbohydrate Content in the Distal Small Intestines

First Posted Date
2017-08-07
Last Posted Date
2020-03-26
Lead Sponsor
University Hospital, Gentofte, Copenhagen
Target Recruit Count
15
Registration Number
NCT03241303
Locations
🇩🇰

Center for Diabetesresearch, Hellerup, Denmark

Cardiovascular Effects of GLP-1 Receptor Activation

First Posted Date
2017-04-05
Last Posted Date
2022-10-18
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
329
Registration Number
NCT03101930
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-12-19
Last Posted Date
2024-12-04
Lead Sponsor
Tracey McLaughlin
Target Recruit Count
9
Registration Number
NCT02996812
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Regulation of Insulin Secretion by the GLP-1 Receptor

First Posted Date
2016-07-26
Last Posted Date
2024-12-12
Lead Sponsor
VA Office of Research and Development
Target Recruit Count
6
Registration Number
NCT02844907
Locations
🇺🇸

Durham VA Medical Center, Durham, NC, Durham, North Carolina, United States

Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2015-09-15
Last Posted Date
2024-12-04
Lead Sponsor
Tracey McLaughlin
Target Recruit Count
10
Registration Number
NCT02550145
Locations
🇺🇸

Stanford University School of Medicine, Stanford, California, United States

Ghrelin Effect on Beta Cell Function in Health and Disease

First Posted Date
2012-11-20
Last Posted Date
2013-04-04
Lead Sponsor
David Dalessio
Target Recruit Count
30
Registration Number
NCT01729299
Locations
🇺🇸

University of Cincinnati, Cincinnati, Ohio, United States

🇺🇸

Cincinnati Children's Hospital and Medical Center, Cincinnati, Ohio, United States

Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2009-02-03
Last Posted Date
2020-06-01
Lead Sponsor
Diva De Leon
Target Recruit Count
14
Registration Number
NCT00835328
Locations
🇺🇸

The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

© Copyright 2024. All Rights Reserved by MedPath