Parsaclisib

Generic Name
Parsaclisib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C20H22ClFN6O2
CAS Number
1426698-88-5
Unique Ingredient Identifier
OS7097575K
Background

Parsaclisib is under investigation in clinical trial NCT03126019 (An Open-Label Study of Parsaclisib in Relapsed or Refractory Follicular Lymphoma (CITADEL-203)).

Associated Conditions
-
Associated Therapies
-

A Study of INCB050465 in Participants With Autoimmune Hemolytic Anemia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-05-25
Last Posted Date
2024-04-10
Lead Sponsor
Incyte Corporation
Target Recruit Count
25
Registration Number
NCT03538041
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

🇺🇸

Weill Medical College of Cornell University, New York, New York, United States

🇮🇹

AZIENDA OSPEDALIERO UNIVERSITARIA MAGGIORE DELLA CARIT� DI NOVARA, Novara, Italy

and more 9 locations

INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

First Posted Date
2018-02-06
Last Posted Date
2022-06-29
Lead Sponsor
Incyte Corporation
Target Recruit Count
50
Registration Number
NCT03424122
Locations
🇺🇸

Baylor Charles A. Sammons Cancer Center, Dallas, Texas, United States

🇺🇸

University of Arizona Cancer Center - Out Pt., Tucson, Arizona, United States

🇺🇸

Texas Oncology, Austin, Texas, United States

and more 18 locations

A Study of INCB050465 in Japanese Subjects With Previously Treated B-Cell Lymphoma (CITADEL-111)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-10-19
Last Posted Date
2023-08-14
Lead Sponsor
Incyte Corporation
Target Recruit Count
17
Registration Number
NCT03314922
Locations
🇯🇵

Cancer Institute Hospital of Jfcr, Koto-ku, Japan

🇯🇵

National Cancer Center Hospital, Tokyo, Japan

🇯🇵

Nagoya City University Hospital, Nagoya, Japan

and more 3 locations

A Study of INCB050465 in Relapsed or Refractory Mantle Cell Lymphoma Previously Treated With or Without a Bruton's Tyrosine Kinase (BTK) Inhibitor

Phase 2
Completed
Conditions
Interventions
First Posted Date
2017-08-01
Last Posted Date
2024-06-24
Lead Sponsor
Incyte Corporation
Target Recruit Count
162
Registration Number
NCT03235544
Locations
🇩🇪

Justus-Liebig University, Giessen, Germany

🇮🇹

A.O.U. Di Modena - Policlinico, Modena, Italy

🇵🇱

University Clinical Center, Gdansk, Poland

and more 100 locations

A Study of INCB050465 in Subjects With Relapsed or Refractory Marginal Zone Lymphoma (CITADEL-204)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2017-05-09
Last Posted Date
2024-07-17
Lead Sponsor
Incyte Corporation
Target Recruit Count
110
Registration Number
NCT03144674
Locations
🇺🇸

Arizona Oncology Associates, Tempe, Arizona, United States

🇺🇸

Sansum Clinic, Santa Barbara, California, United States

🇺🇸

UCLA Healthcare Hematology-Oncology, Santa Monica, California, United States

and more 82 locations

A Study of INCB050465 in Relapsed or Refractory Follicular Lymphoma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2017-04-24
Last Posted Date
2024-07-10
Lead Sponsor
Incyte Corporation
Target Recruit Count
126
Registration Number
NCT03126019
Locations
🇺🇸

Florida Cancer Specialists & Research Institute, Fort Myers, Florida, United States

🇺🇸

Hattiesburg Clinic Hematology, Hattiesburg, Mississippi, United States

🇺🇸

University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States

and more 80 locations

Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-02-01
Last Posted Date
2021-12-02
Lead Sponsor
Incyte Corporation
Target Recruit Count
26
Registration Number
NCT03039114
Locations
🇮🇹

UO Ematologia ASST Spedali Civili, Brescia, Italy

🇺🇸

Clinical Research Alliance, Lake Success, New York, United States

🇺🇸

University of Kansas Cancer Center, Fairway, Kansas, United States

and more 18 locations

A Phase 2 Safety and Efficacy Study of INCB050465 in Subjects With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (CITADEL-202)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2016-12-20
Last Posted Date
2022-03-10
Lead Sponsor
Incyte Corporation
Target Recruit Count
60
Registration Number
NCT02998476
Locations
🇺🇸

Asclepes Research Centers, Weeki Wachee, Florida, United States

🇺🇸

Arizona Oncology Associates, PC - HAL, Tempe, Arizona, United States

🇦🇺

Flinders Medical Centre, Bedford Park, South Australia, Australia

and more 67 locations

A Study of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

First Posted Date
2016-03-24
Last Posted Date
2024-05-01
Lead Sponsor
Incyte Corporation
Target Recruit Count
74
Registration Number
NCT02718300
Locations
🇺🇸

California Cancer Associates For Research and Excellence, Fresno, California, United States

🇺🇸

Baylor Scott and White Research Institute, Dallas, Texas, United States

🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

and more 36 locations

Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumors

First Posted Date
2016-01-06
Last Posted Date
2022-03-31
Lead Sponsor
Incyte Corporation
Target Recruit Count
159
Registration Number
NCT02646748
Locations
🇺🇸

John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, California, United States

🇺🇸

Georgetown University Medical Center Lombardi CCC, Washington, District of Columbia, United States

🇺🇸

The Center for Cancer and Blood Disorders (RCCA MD LLC-Maryland Vidision), Bethesda, Maryland, United States

and more 14 locations
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