Flortaucipir F-18
- Generic Name
- Flortaucipir F-18
- Brand Names
- Tauvid
- Drug Type
- Small Molecule
- Chemical Formula
- C16H10FN3
- CAS Number
- 1522051-90-6
- Unique Ingredient Identifier
- T1JP1KYU9O
- Background
Flortaucipir F-18, also known as F-T807 and F-AV-1451, is a small indole molecule synthesized with a radioactive fluorine isotope. It is used as a marker in positron emission tomography (PET) imaging of patients suspected of having Alzheimer's disease. After crossing the blood-brain barrier, flortaucipir F-18 binds to aggregated tau protein, a hallmark of Al...
- Indication
Flortaucipir F-18 is a radioactive agent indicated for positron emission tomography (PET) imaging of aggregated tau neurofibrillary tangles (NFTs) in adult patients under evaluation for Alzheimer's disease. Flortaucipir F-18 is not indicated for use in patients under evaluation for chronic traumatic encephalopathy.
- Associated Conditions
- Alzheimer's Disease (AD)
- Associated Therapies
- -
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2024-03-07
- Last Posted Date
- 2024-12-03
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 32
- Registration Number
- NCT06297590
- Locations
- 🇺🇸
K2 Medical Research, LLC, Maitland, Florida, United States
🇺🇸Charter Research, LLC, The Villages, Florida, United States
🇺🇸CenExel iResearch, LLC (CenExel iRA), Decatur, Georgia, United States
Exploratory Evaluation of Flortaucipir Injection in Healthy Volunteers and Cognitively Impaired Subjects
- Conditions
- Interventions
- First Posted Date
- 2020-07-16
- Last Posted Date
- 2020-09-25
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 36
- Registration Number
- NCT04474405
- Locations
- 🇺🇸
Hoag Memorial Hospital Presbyterian, Newport Beach, California, United States
🇺🇸WCCT Global, LLC, Cypress, California, United States
Flortaucipir PET Imaging in the Preclinical, Prodromal and Dementia Phases of Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2020-07-13
- Last Posted Date
- 2020-09-25
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 89
- Registration Number
- NCT04468347
Evaluation of Flortaucipir PET Signal and Cognitive Change in Early Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2019-04-03
- Last Posted Date
- 2020-08-28
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 205
- Registration Number
- NCT03901105
- Locations
- 🇺🇸
American College of Radiology, Philadelphia, Pennsylvania, United States
A Reader Study to Assess Accuracy and Reliability of Flortaucipir F 18 Positron Emission Tomography (PET) Scan Interpretation
- First Posted Date
- 2019-04-03
- Last Posted Date
- 2020-09-09
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 242
- Registration Number
- NCT03901092
- Locations
- 🇺🇸
American College of Radiology, Philadelphia, Pennsylvania, United States
Tau Screening Study in Subjects With Early Symptomatic AD
- Conditions
- Interventions
- First Posted Date
- 2018-03-16
- Last Posted Date
- 2020-08-24
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 161
- Registration Number
- NCT03467477
- Locations
- 🇺🇸
Progressive Medical Research, Port Orange, Florida, United States
🇺🇸Renstar Medical Research, Ocala, Florida, United States
🇺🇸Cotton O'neil Clinical Research Center, Topeka, Kansas, United States
Tau Screening Study in Patients With Early Symptomatic AD
- Conditions
- Interventions
- First Posted Date
- 2017-10-26
- Last Posted Date
- 2020-08-24
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 155
- Registration Number
- NCT03322462
- Locations
- 🇺🇸
The Memory Clinic, Bennington, Vermont, United States
🇨🇦Toronto Memory Program, Toronto, Ontario, Canada
🇺🇸Boston Center for Memory, Newton, Massachusetts, United States
Flortaucipir 18F PET Imaging in BIOCARD Study
- Conditions
- Interventions
- First Posted Date
- 2017-02-14
- Last Posted Date
- 2020-09-25
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 23
- Registration Number
- NCT03052972
- Locations
- 🇺🇸
Johns Hopkins Hospital, Baltimore, Maryland, United States
Flortaucipir PET Imaging in Subjects With FTD
- Conditions
- Interventions
- First Posted Date
- 2017-02-02
- Last Posted Date
- 2020-09-25
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 16
- Registration Number
- NCT03040713
- Locations
- 🇺🇸
Movement Disorder Center, UCSD, La Jolla, California, United States
🇺🇸Memory and Aging Center, UCSF, San Francisco, California, United States
🇺🇸UT Southwestern Medical Center, Dallas, Texas, United States
A Study of LY3303560 in Participants With Mild Cognitive Impairment or Alzheimer's Disease
- Conditions
- Interventions
- First Posted Date
- 2017-01-12
- Last Posted Date
- 2023-10-10
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 22
- Registration Number
- NCT03019536
- Locations
- 🇯🇵
For additional information regarding investigative sites for this trial, contact 1-888-545-5972 Mon - Fri, 9 AM to 4 PM or 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri, 9 AM to 5 PM Eastern Time or speak with your personal physician., Kurume, Japan
🇺🇸Bioclinica, The Villages, Florida, United States
🇬🇧For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., London, United Kingdom
Drug Development Updates
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