Selonsertib

Generic Name
Selonsertib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C24H24FN7O
CAS Number
1448428-04-3
Unique Ingredient Identifier
NS3988A2TC
Background

Selonsertib is under investigation in clinical trial NCT03053050 (Safety and Efficacy of Selonsertib in Adults With Nonalcoholic Steatohepatitis (NASH) and Bridging (F3) Fibrosis).

Associated Conditions
-
Associated Therapies
-

Selonsertib in Combination With Prednisolone Versus Prednisolone Alone in Participants With Severe Alcoholic Hepatitis (AH)

First Posted Date
2016-08-03
Last Posted Date
2019-02-06
Lead Sponsor
Gilead Sciences
Target Recruit Count
104
Registration Number
NCT02854631
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Washington, Seattle, Washington, United States

๐Ÿ‡จ๐Ÿ‡ฆ

Toronto General Hospital, Toronto, Ontario, Canada

๐Ÿ‡บ๐Ÿ‡ธ

University of Pennsylvania, Philadelphia, Pennsylvania, United States

and more 41 locations

Study to Evaluate the Pharmacokinetics of Selonsertib in Participants With Normal and Impaired Hepatic Function

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-07-28
Last Posted Date
2021-01-27
Lead Sponsor
Gilead Sciences
Target Recruit Count
52
Registration Number
NCT02509624

Selonsertib in Adults With Pulmonary Arterial Hypertension

First Posted Date
2014-09-09
Last Posted Date
2019-04-10
Lead Sponsor
Gilead Sciences
Target Recruit Count
151
Registration Number
NCT02234141
Locations
๐Ÿ‡บ๐Ÿ‡ธ

VA Greater Los Angeles Healthcare System, Los Angeles, California, United States

๐Ÿ‡จ๐Ÿ‡ฆ

University Health Network, Toronto, Ontario, Canada

๐Ÿ‡บ๐Ÿ‡ธ

University of Minnesota, Minneapolis, Minnesota, United States

and more 43 locations

Efficacy, Safety, and Tolerability of Selonsertib (GS-4997) in Participants With Diabetic Kidney Disease

First Posted Date
2014-06-30
Last Posted Date
2019-11-05
Lead Sponsor
Gilead Sciences
Target Recruit Count
334
Registration Number
NCT02177786
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Northwest Louisiana Nephrology, Shreveport, Louisiana, United States

๐Ÿ‡บ๐Ÿ‡ธ

Pines Clinical Research Inc., Pembroke Pines, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Florida Pulmonary Research Institute, Winter Park, Florida, United States

and more 98 locations
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