PF-06650833

Generic Name
PF-06650833
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H20FN3O4
CAS Number
1817626-54-2
Unique Ingredient Identifier
S3F315JJXI
Background

PF-06650833 is under investigation in clinical trial NCT02609139 (Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects).

Associated Conditions
-
Associated Therapies
-

A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC)

First Posted Date
2021-10-01
Last Posted Date
2023-10-02
Lead Sponsor
Pfizer
Target Recruit Count
10
Registration Number
NCT05064332
Locations
πŸ‡ΊπŸ‡Έ

Qps-Mra, Llc, South Miami, Florida, United States

IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.

First Posted Date
2021-06-22
Last Posted Date
2021-06-22
Lead Sponsor
Giovanni Franchin, M.D, Ph.D
Target Recruit Count
68
Registration Number
NCT04933799
Locations
πŸ‡ΊπŸ‡Έ

Bronx-Lebanon Hospital Center Health Care System, Bronx, New York, United States

IRAK4 Inhibition in Treatment of COVID-19 With ARDS (I-RAMIC)

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2020-10-05
Last Posted Date
2021-10-26
Lead Sponsor
Yale University
Target Recruit Count
7
Registration Number
NCT04575610
Locations
πŸ‡ΊπŸ‡Έ

Yale New Haven Hospital, New Haven, Connecticut, United States

TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE

First Posted Date
2020-06-04
Last Posted Date
2023-04-07
Lead Sponsor
Pfizer
Target Recruit Count
460
Registration Number
NCT04413617
Locations
πŸ‡§πŸ‡¬

Independent Medical Diagnostic Laboratory Mediscan EOOD, Plovdiv, Bulgaria

πŸ‡§πŸ‡¬

MHAT Plovdiv AD, Plovdiv, Bulgaria

πŸ‡§πŸ‡¬

DCC Sveti Georgi EOOD, Plovdiv, Bulgaria

and more 140 locations

A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa

First Posted Date
2019-09-17
Last Posted Date
2023-06-15
Lead Sponsor
Pfizer
Target Recruit Count
194
Registration Number
NCT04092452
Locations
πŸ‡ΊπŸ‡Έ

Boston Medical Center, Boston, Massachusetts, United States

πŸ‡ΊπŸ‡Έ

Dermatology Associates of Seattle, Seattle, Washington, United States

πŸ‡ΊπŸ‡Έ

Dawes Fretzin Clinical Research Group, LLC, Indianapolis, Indiana, United States

and more 72 locations

Bioavailability and Food Effect Study of Two Formulations of PF-06650833

Phase 1
Completed
Conditions
Interventions
First Posted Date
2017-10-12
Last Posted Date
2019-04-19
Lead Sponsor
Pfizer
Target Recruit Count
24
Registration Number
NCT03308110
Locations
πŸ‡§πŸ‡ͺ

Pfizer Clinical Research Unit, Brussels, Belgium

Safety and Efficacy of Pf-06650833 In Subjects With Rheumatoid Arthritis, With An Inadequate Response To Methotrexate

First Posted Date
2016-12-19
Last Posted Date
2020-02-27
Lead Sponsor
Pfizer
Target Recruit Count
269
Registration Number
NCT02996500
Locations
πŸ‡ΊπŸ‡Έ

Arthritis & Rheumatic Care Center, South Miami, Florida, United States

πŸ‡ΊπŸ‡Έ

Medical Associates of North Georgia, Canton, Georgia, United States

πŸ‡ΊπŸ‡Έ

Millennium Research, Ormond Beach, Florida, United States

and more 96 locations

Study for MR Formulation of PF-06650833 in Healthy Adult Japanese Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-10-18
Last Posted Date
2018-10-05
Lead Sponsor
Pfizer
Target Recruit Count
10
Registration Number
NCT02936154
Locations
πŸ‡―πŸ‡΅

P-one Clinic, Keikokai Medical Corporation, Hachioji-shi, Tokyo, Japan

Study to Evaluate Pharmacokinetics of A Modified Release Formulation of PF-06650833 in Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-11-20
Last Posted Date
2016-05-09
Lead Sponsor
Pfizer
Target Recruit Count
18
Registration Number
NCT02609139
Locations
πŸ‡ΊπŸ‡Έ

New Haven Clinical Research Unit, New Haven, Connecticut, United States

Study To Evaluate The Safety, Tolerability, And Pharmacokinetics Of Oral Pf-06650833 In Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-06-30
Last Posted Date
2018-04-19
Lead Sponsor
Pfizer
Target Recruit Count
71
Registration Number
NCT02485769
Locations
πŸ‡ΊπŸ‡Έ

Pfizer New Haven Clinical Research Unit, New Haven, Connecticut, United States

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