FLX475

Generic Name
FLX475
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
-
Background

FLX475 is a small molecule CCR4 antagonist being investigated for the treatment of cancer.

Associated Conditions
-
Associated Therapies
-

FLX475 in Combination With Ipilimumab in Advanced Melanoma

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2021-05-20
Last Posted Date
2023-12-05
Lead Sponsor
RAPT Therapeutics, Inc.
Target Recruit Count
6
Registration Number
NCT04894994
Locations
🇺🇸

Washington University School of Medicine St. Louis, Saint Louis, Missouri, United States

🇺🇸

University of California, Los Angeles, Los Angeles, California, United States

🇺🇸

Moffitt Cancer Center, Tampa, Florida, United States

and more 1 locations

FLX475 Combined With Pembrolizumab in Patients With Advanced or Metastatic Gastric Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2021-02-24
Last Posted Date
2023-12-26
Lead Sponsor
Hanmi Pharmaceutical Company Limited
Target Recruit Count
20
Registration Number
NCT04768686
Locations
🇰🇷

The Catholic University of Korea St. Vincent Hospital, Suwon-si,, Gyeonggi-do, Korea, Republic of

🇰🇷

Chonnam National University Hwasun Hospital, Hwasun, Jeollanam-do, Korea, Republic of

🇰🇷

Hanllym University Medical Center, Anyang-si, Gyeonggi-do, Korea, Republic of

and more 7 locations

Dose Escalation and Expansion Study of FLX475 Monotherapy and in Combination With Pembrolizumab

Phase 1
Active, not recruiting
Conditions
Interventions
First Posted Date
2018-09-17
Last Posted Date
2024-04-16
Lead Sponsor
RAPT Therapeutics, Inc.
Target Recruit Count
323
Registration Number
NCT03674567
Locations
🇭🇰

Prince of Wales Hospital, Shatin, Hong Kong

🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

🇺🇸

University of Washington, Seattle, Washington, United States

and more 32 locations
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