Ladarixin

Generic Name
Ladarixin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C11H12F3NO6S2
CAS Number
849776-05-2
Unique Ingredient Identifier
DEH7Q6472O
Background

Ladarixin is under investigation in clinical trial NCT04628481 (A Study of Oral Ladarixin in New-onset Type 1 Diabetes and a Low Residual Β-Cell Function).

Associated Conditions
-
Associated Therapies
-

Ladarixin With Sotorasib in Advanced NSCLC - Phase II

First Posted Date
2023-04-18
Last Posted Date
2024-03-29
Lead Sponsor
NYU Langone Health
Registration Number
NCT05815186
Locations
🇺🇸

NYU Langone Health, New York, New York, United States

Ladarixin With Sotorasib in Advanced NSCLC

First Posted Date
2023-04-18
Last Posted Date
2024-03-29
Lead Sponsor
NYU Langone Health
Target Recruit Count
40
Registration Number
NCT05815173
Locations
🇺🇸

NYU Langone Health, New York, New York, United States

Clinical Trial on Ladarixin Adjunctive Therapy to Improve Glycemic Control in Type 1 Diabetes.

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2022-05-10
Last Posted Date
2023-12-22
Lead Sponsor
Dompé Farmaceutici S.p.A
Target Recruit Count
2
Registration Number
NCT05368402
Locations
🇮🇹

Ospedale F. Spaziani Frosinone, Frosinone, Italy

🇮🇹

Università Campus Bio-Medico di Roma (UCBM) Policlinico Universitario, Rome, Italy

Ladarixin as Adjunctive Therapy to Improve Insulin Sensitivity and Glucometabolic Outcomes in Type 1 Diabetes

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2021-09-05
Last Posted Date
2023-12-22
Lead Sponsor
Dompé Farmaceutici S.p.A
Registration Number
NCT05035368
Locations
🇺🇸

Institute of Cellular Therapeutics Allegheny Health Network, Pittsburgh, Pennsylvania, United States

A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline.

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2021-05-24
Last Posted Date
2023-12-22
Lead Sponsor
Dompé Farmaceutici S.p.A
Target Recruit Count
25
Registration Number
NCT04899271
Locations
🇩🇪

Institut fuer Diabetes forschung in Muenster (IDFM), Muenster, Germany

🇮🇹

Universitá degli Studi di Milano - Ospedale Luigi Sacco, Milan, Italy

🇩🇪

Universitaetsklinikum Gessen und Marburg GmbH - Medizinische Klinik und Poliklinik III, Glessen, Germany

and more 13 locations

A Single Dose Study About the Influence of Food on the Oral Bioavailability of Ladarixin Capsule in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2021-04-22
Last Posted Date
2024-01-17
Lead Sponsor
Dompé Farmaceutici S.p.A
Target Recruit Count
36
Registration Number
NCT04854642
Locations
🇨🇭

CROSS Research S.A., I Unit, Arzo, Canton Ticino, Switzerland

A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2020-11-13
Last Posted Date
2024-11-07
Lead Sponsor
Dompé Farmaceutici S.p.A
Target Recruit Count
140
Registration Number
NCT04628481
Locations
🇺🇸

Atlanta Diabetes Associates (ADA), Atlanta, Georgia, United States

🇺🇸

UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States

🇧🇪

Universitair Ziekenhuis Brussel (UZB), Jette, Belgium

and more 53 locations

A Phase 2, Multicentre, Randomized, Double-blind, Placebo-controlled Study in Patients With New-onset Type 1 Diabetes

First Posted Date
2016-06-28
Last Posted Date
2024-04-19
Lead Sponsor
Dompé Farmaceutici S.p.A
Target Recruit Count
76
Registration Number
NCT02814838
Locations
🇩🇪

Med. Klinik und Poliklinik 3, Universitätsklinikum Giessen und Marburg GmbH, Giessen, Germany

🇧🇪

Universitair Ziekenhuis Brussel Diabetes Clinic, Brussels, Belgium

🇧🇪

Universitair Ziekenhuis Leuven Campus Gasthuisberg Endocrinology, Leuven, Belgium

and more 5 locations
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