Rezafungin

Generic Name
Rezafungin
Brand Names
Rezzayo
Drug Type
Small Molecule
Chemical Formula
C63H85N8O17
CAS Number
1396640-59-7
Unique Ingredient Identifier
G013B5478J
Background

Rezafungin is an echinocandin antifungal drug. Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily....

Indication

Rezafungin is indicated in patients 18 years of age or older who have limited or no alternative options for the treatment of candidemia and invasive candidiasis.

Associated Conditions
Candidemia, Invasive Candidiasis
Associated Therapies
-

Rezafungin Pharmacokinetics in Patients on ECMO

Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2024-03-26
Last Posted Date
2024-12-17
Lead Sponsor
Hartford Hospital
Target Recruit Count
8
Registration Number
NCT06329518
Locations
🇺🇸

Hartford Hospital, Hartford, Connecticut, United States

Safety and Pharmacokinetics of Rezafungin

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2019-10-07
Last Posted Date
2021-07-16
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
14
Registration Number
NCT04117607
Locations
🇺🇸

ICON Early Phase Services Clinical Research Unit, San Antonio, Texas, United States

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