Tilsotolimod

Generic Name
Tilsotolimod
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1948266-37-2
Unique Ingredient Identifier
G287IC9MH3
Background

Tilsotolimod is under investigation in clinical trial NCT03865082 (Study of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)).

Associated Conditions
-
Associated Therapies
-

Intratumoral Tilsotolimod, a TLR-9 Agonist, Together With Intratumoral Ipilimumab and Intravenous Nivolumab in Patients With Advanced Cancers

First Posted Date
2020-02-17
Last Posted Date
2024-10-18
Lead Sponsor
Gustave Roussy, Cancer Campus, Grand Paris
Target Recruit Count
25
Registration Number
NCT04270864
Locations
๐Ÿ‡ซ๐Ÿ‡ท

Gustave Roussy, Villejuif, Val De Marne, France

A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-368 Plus Tilsotolimod and Other Therapy Combinations in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

First Posted Date
2019-12-12
Last Posted Date
2023-02-27
Lead Sponsor
AbbVie
Target Recruit Count
30
Registration Number
NCT04196283
Locations
๐Ÿ‡บ๐Ÿ‡ธ

The University of Chicago Medical Center /ID# 217196, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

MD Anderson Cancer Center /ID# 214041, Houston, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Norton Cancer Institute /ID# 216179, Louisville, Kentucky, United States

and more 23 locations

A Randomized Controlled Phase II Trial With Intradermal IMO-2125 in Pathological Tumor Stage (p) T3-4 cN0M0 Melanoma

First Posted Date
2019-10-15
Last Posted Date
2021-04-15
Lead Sponsor
A.J.M. van den Eertwegh
Target Recruit Count
214
Registration Number
NCT04126876
Locations
๐Ÿ‡ณ๐Ÿ‡ฑ

VU Medical Centere, Amsterdam, Netherlands

Study of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2019-03-06
Last Posted Date
2022-02-17
Lead Sponsor
Idera Pharmaceuticals, Inc.
Target Recruit Count
30
Registration Number
NCT03865082
Locations
๐Ÿ‡บ๐Ÿ‡ธ

MD Anderson Cancer Center, Houston, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Southern California/ Hoag Hospital Presbyterian, Newport Beach, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Banner University Medical Center Tucson Campus, Tucson, Arizona, United States

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