MAS825

Generic Name
MAS825
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
-
Associated Conditions
-
Associated Therapies
-

A Single-patient Clinical Trial of MAS825 in a Patient With XIAP Deficiency

First Posted Date
2024-03-13
Last Posted Date
2024-03-13
Lead Sponsor
The Hospital for Sick Children
Target Recruit Count
1
Registration Number
NCT06309823
Locations
🇨🇦

The Hospital for Sick Children, Toronto, Ontario, Canada

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Clonal Hematopoiesis of Indeterminate Potential (CHIP)

First Posted Date
2023-10-24
Last Posted Date
2024-12-10
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
28
Registration Number
NCT06097663
Locations
🇺🇸

Washington University, Saint Louis, Missouri, United States

🇺🇸

Vanderbilt University Medical Cent, Nashville, Tennessee, United States

🇩🇪

Novartis Investigative Site, Muenchen, Germany

A First-in-human Study to Investigate the Safety, Tolerability and Pharmacokinetics of MAS825 in Healthy Volunteers

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-12-11
Last Posted Date
2022-09-30
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
80
Registration Number
NCT04665154
Locations
🇬🇧

Novartis Investigative Site, Mere Way, Nottingham, United Kingdom

Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations

First Posted Date
2020-11-23
Last Posted Date
2024-11-26
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
17
Registration Number
NCT04641442
Locations
🇺🇸

Cincinnati Children's Hospital, Cincinnati, Ohio, United States

🇺🇸

Children´s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Texas Children´s Hospital, Houston, Texas, United States

and more 7 locations

Study of Efficacy and Safety of MAS825 in Patients With COVID-19

First Posted Date
2020-05-11
Last Posted Date
2022-08-10
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
140
Registration Number
NCT04382651
Locations
🇺🇸

Novartis Investigative Site, Mesquite, Texas, United States

Study of Efficacy and Safety of Investigational Treatments in Patients With Moderate to Severe Hidradenitis Suppurativa

First Posted Date
2019-02-01
Last Posted Date
2024-08-27
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
248
Registration Number
NCT03827798
Locations
🇺🇸

Olympian Clinical Research ., Clearwater, Florida, United States

🇺🇸

Park Avenue Dermatology, PA, Orange Park, Florida, United States

🇺🇸

Advanced Medical Research, Sandy Springs, Georgia, United States

and more 6 locations
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