Phorbol 12-myristate 13-acetate diester

Generic Name: Phorbol 12-myristate 13-acetate diester

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₃₆H_₅₆O_₈

CAS Number: 16561-29-8

Unique Ingredient Identifier: NI40JAQ945

Background: Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).

Associated Conditions: -

Associated Therapies: -

Clinical Trials

Phase II Study of TPA Plus Dexamethasone & CMT in Hematologic Malignancies

Phase 2

Terminated

Conditions: Leukemia

Interventions: Drug: 12-O-tetradecanoylphorbol-13-acetate
Drug: Dexamethasone
Drug: Choline magnesium trisalicylate

First Posted Date: 2009-11-09

Last Posted Date: 2015-11-04

Lead Sponsor: Rutgers, The State University of New Jersey

Target Recruit Count: 1

Registration Number: NCT01009931

Locations: 🇺🇸
Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder

Phase 1

Terminated

Conditions: Chronic Myeloproliferative Disorders
Leukemia
Lymphoma
Multiple Myeloma and Plasma Cell Neoplasm
Myelodysplastic Syndromes
Myelodysplastic/Myeloproliferative Diseases
Precancerous/Nonmalignant Condition

First Posted Date: 2003-01-27

Last Posted Date: 2010-01-26

Lead Sponsor: University of Medicine and Dentistry of New Jersey

Registration Number: NCT00004058

Locations: 🇺🇸
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School, New Brunswick, New Jersey, United States

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